A new protein factor named PF2 was recently isolated from mammalian cell nuclei. Among other protein domains, PF2 exhibits an RPD3-interacting domain (RPD3 contains the catalytic activity of the HDAC B complex) and a TFS-interacting domain (TFS is a DNA binding protein). PF2 does not have a DNA binding domain, however. Predict a likely function of PF2 and justify it. The importance of both domains should be explained.

Answers

Answer 1

Answer:

The likely functions of  PF2 includes binding of several protein factors and DNA structure formation

Explanation:

PF2 contains RPD3 and TFS domains

The likely functions of  PF2 includes binding and DNA structure formation

For the RPD3 domain that contains the  catalytic activity of the HDAC B complex its function is to interact with other protein factors by binding with them and carrying out the  process of the signaling cascade.

while the TFS - interacting domain have likely functions like ; DNA replication, DNA repair and storage. It also has the function involving the DNA structure


Related Questions

Analyze the relationships between the anatomical structures and physiological functions of the muscular system by matching the terms in column A with the definitions in column B. Place the letter of your choice in the space provided. Column A
a. Endomysium
b. Epimysium
c. Fascia
d. Fascicle
e. Myosin
f. Perimysium
g. Sarcolemma
h. Sarcomere
i. Sarcoplasm
j. Sarcoplasmic reticulum
k. Tendon
l. Transverse (T) tubule reticulum
Column B
1. Membranous channel extending inward from muscle fiber membrane
2. Cytoplasm of a muscle fiber
3. Connective tissue located between adjacent muscles
4. Layer of connective tissue that separates a muscle into small bundles
5. Plasma membrane of a muscle fiber
6. Layer of connective tissue that surrounds a skeletal muscle
7. Unit of alternating light and dark striations between discs (lines)
8. Layer of connective tissue that surrounds an individual muscle fiber
9. Cellular organelle in muscle fiber corresponding to the endoplasmic
10. Cordlike part that attaches a muscle to a bone
11. Protein found within thick filament
12. A small bundle of muscle fibers within a muscle

Answers

Answer:

a. Endomysium 8. The layer of connective tissue that surrounds an individual muscle fiber

b. Epimysium 6. The layer of connective tissue that surrounds a skeletal muscle

c. Fascia 3. Connective tissue located between adjacent muscles

d. Fascicle 12. A small bundle of muscle fibers within a muscle

e. Myosin 11. Protein found within a thick filament

f. Perimysium 4. The layer of connective tissue that separates a muscle into small bundles

g. Sarcolemma 5. The plasma membrane of a muscle fiber

h. Sarcomere 7. Unit of alternating light and dark striations between discs (lines)

i. Sarcoplasm 2. The cytoplasm of a muscle fiber

j. Sarcoplasmic reticulum 9. A cellular organelle in muscle fiber corresponding to the endoplasmic

k. Tendon 10. The cordlike part that attaches a muscle to a bone

l. Transverse (T) tubule reticulum 1. Membranous channel extending inward from muscle fiber membrane

Explanation:

A muscle has around it epimysium, which is connective tissue. Inside the epimysium, there are fascicles, and around each of them, there is perimysium. Inside every fascicle, there are muscle fibers, each of them is surrounded by a connective tissue called endomysium. Between every muscle, there is also connective tissue and is called fascia. The connective tissue has vessels and provides support.

The muscle cells are called fibers. They have a membrane, the sarcolemma, a cytoplasm, the sarcoplasm, and a sarcomere, which is the functional unit of the fiber, in other words, it is the structure responsible for the contraction. The sarcomere has different bands made of thick filaments of myosin and thin filaments of actin. They are the light and dark striations that go from disc z to disc z when we observe the sarcomere under a special microscope. The sarcoplasmic reticulum is the place that stores the calcium necessary for the contraction of the fiber, and the transverse tubule reticulum allows the contraction of various fibers since they spread the action potential amongst fibers.

How is gamete formation different in females than in males?

a) Males produce four functional sperm while females produce only one functional egg.
b) Males produce only one functional sperm while females produce four functional eggs.
c) Males produce four genetically identical sperm while females produce four genetically different eggs.
d) Males produce four genetically different sperm while females produce four genetically identical eggs.

Answers

I think it’s (d) I’m really sorry if I’m wrong
I think it’s d I’m sorry if it’s incorrect

Oceans have a high Biodiversity.


true


false

Answers

(つ ^_^ )つ Hey There!

Answer : True!

If the acidity of the body rises, excess [BLANK] ion are secreted into the collecting ducts

Answers

Answer:

our body are important to take care

Which organism will have DNA most similar to the turtle?

Answers

Answer:

the answer is leopards!

Explanation:

I answered a similar question like this yesterday,

Hope it helps!!

The organism that will have DNA most similar to the turtle's will be other reptiles, particularly those in the same order as turtles, which is Testudines, which is present in Option A.

What is DNA sharing among ancestors?

Organisms that are closely related evolutionarily tend to have more similar DNA sequences than those that are more distantly related because they share a more recent common ancestor and have had less time to accumulate genetic differences. Turtles belong to the class Reptilia, which includes other reptiles like lizards, snakes, crocodiles, and birds. Within the reptile class, turtles are classified under the order Testudines, and other members of this order include tortoises and terrapins that share common characteristics with turtles.

Hence, the organism that will have DNA most similar to the turtle's will be other reptiles, particularly those in the same order as the turtles present in Option A.

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question is incomplete, complete question is below

Which organism will have DNA most similar to the turtle?

A)reptiles

B)fish

Answer of the question

Answers

I can’t really see the question

Find the speed of a caterpillar that crawls a distance of 6.0 cm every
2.0 seconds. The equation for speed is v=d/t.

Answers

Answer:

3 cm per second

Explanation:

6/2=3 cm per second

A tissue is composed of a group of

Answers

Answer:

Tissue is a group of cells that have similar structure and that function together as a unit. primary types of body tissues include epithelial, connective, muscular and nervous tissues. Epithelial tissues form the covering of all body surfaces , ine body, cavities and hollow organs, and are the major tissues in glands.

A tissue is composed of a group of cells that are determined to play a specific function. The Cytoplasm is a dense gel-like material that is filled within the cell.

What is Cell theory?

Cell theory was proposed by M. Schleiden and T. Schwann in 1838. According to them, there are three postulates of cell theory that are as follows:

All living organisms whether plants or animals are made up of cells.A cell is the smallest unit of all living organisms.The cell is the structural and functional unit of life.

Cell theory was further refined by German biologist Rudolf Virchow in 1855. According to him, all cells are arising from pre-existing cells. The Cell wall generally protects the cell and it is most commonly found in plants, animals, bacteria, etc.

Inside the cell, there are various organelles present that perform specific functions for the survival of the cells. The nucleus is known as the brain or controlling center of the cell, which transmits genetic information from one generation to the next.

Therefore, each of the above-given term is justified above.

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Which of the following is an inherited trait?


A. Freckles
B. Being a good reader
C. A birthmark
D. A scar

Answers

Answer:

A. freckles

Explanation:

inherited traits are things you are born with that resemble your parents like freckles, color hair and skin even eyes and other such things

The inheritance of traits depends on the genes, not on the somatic cells. In the given choices, freckles are inherited from parents to offspring.

What are freckles?

Freckles are caused by either sun or by genes. The presence of this can be due to the genes carrying it.

Genetics and sun exposure is the main cause of freckles. There are a number of genes involved, and they can interact with one another in lots of different ways.

Somatic variations are not likely to get inherited.

Thus, the correct option is A.

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HELP BIOLOGY 50 POINTS !!!!!!
Biology fill in the blanks
below i attatched the blanks you have to fill
heres the words you have to use
-
lactase
repressor
transcribe
dairy products
e.coli
rna polymerase
operator
transcription
repressor
operator
lactose intolerant
protein
enzymes
bases
--
in the answer just put - the # and the answer for each blank
WILL GIVE BRAINLIEST

Answers

Answer:

1. lactose intolerant

2. lactase

3. dairy products

4. e.coli

5. enzymes

6. protein

7. repressor

8. operator

9. rna polymerase

10. transcribe

11. bases

12. repressor

13. operator

14. transcription

Homologous recombination occurs in a heterozygote in which alleles D and d differ by a single base pair. The D allele has a G (a GC base pair) at one position, whereas the d allele has a C (a CG base pair) at the same position. If branch migration causes heteroduplex formation across this position, what is the expected outcome

Answers

Answer:

Mismatch DNA repair mechanism recognizes the abnormal base pairing (G-G base pair) and may correct it by converting the D allele to d

Explanation:

The DNA mismatch repair can be defined as a specialized mechanism that recognizes and repairs errors in the nuclotide sequence (such as, for example, bases erroneously incorporated) during DNA replication and recombination. The DNA mismatch repair is a system that also acts to repair the DNA after damage. It has been shown that the DNA mismatch repair mechanism leads to the generation of a DNA molecule with one chain that has the nucleotide sequence arising from DNA repair and one parental chain. In this case, it is expected that the DNA mismatch repair mechanism will identify the abnormal G-G base pairing and then this system may change the D allele to a d allele by introducing a C base instead of a G base in the DNA strand.

Mosses and other bryophytes are quite short, while many ferns, cone-bearing plants, and flowering plants can grow quite tall. Which type of tissue found in the taller plants, but not in mosses, is most useful for explaining the tall heights that plants can achieve? *

A. endosperm, which nurtures the developing plant embryo in a seed
B. leaf epidermis, which protects inner leaf tissues from drying out.
C. vascular tissues, which conduct water and nutrients against the pull of gravity
D. apical meristems, which allow growth in the tips of roots and shoots

Answers

Answer: C. Vascular tissues, which conduct water and nutrients against the pull of gravity.

Explanation:

Because Moss and other bryophytes lack vascular tissue and sharing a number of other primitive traits.

BIOLOGY CIRCULATORY SYSTEM!! WILL NAME BRAINLIEST IF YOU ANSWER CORRECTLY!!

Answers

Answer:

Q1)Heart,Lungs,Arteries,Veins,Vessels

Q2)Blood vessels flow blood throughout the body. Arteries transport blood away from the heart. Veins return blood back toward the heart. Capillaries surround body cells and tissues to deliver and absorb oxygen, nutrients, and other substances.

Please mark me brainliest.

Explanation:

What is the function of the circulatory system. I forgot!

Answers

Answer:

to pump blood throughout the body

Answer:

to pump blood throughout the body

Explanation:

The circulatory system contains of arteries and veins that help blood travel throughout the body

biological term for the germ layer that gives rise to the nervous system​

Answers

The three germ layers are the endoderm, the ectoderm, and the mesoderm. Cells in each germ layer differentiate into tissues and embryonic organs. The ectoderm gives rise to the nervous system and the epidermis, among other tissues. The mesoderm gives rise to the muscle cells and connective tissue in the body.

What are three ways in which Mountains can be impacted by either natural processes or human processes, including both constructive and destructive processes? Please write if it is constructive or destructive next to it.

I need answers quickly, please!
I will rate brainliest

Answers

Answer:

deposition-dropping of sediments (Destructive)

mountain building-tectonic plate (Constructive)

movement

volcanic activity (Desctrutive)

Amino acids are joined by dehydration synthesis and link by a blank bond.

Answers

Answer:

What is the question?? :}

Explanation:

how is mitosis different from mitosis ​

Answers

Answer:

Mitosis produces two diploid (2n) somatic cells that are genetically identical to each other and the original parent cell, whereas meiosis produces four haploid (n) gametes that are genetically unique from each other and the original parent (germ) cell.

When the hilum of the kidney faces anteriorly, posteriorly, or laterally instead of medially, it is called

Answers

Answer:

Answer: skeletal system. When the hilum of the kidney faces anteriorly, posteriorly, or laterally instead of medially, it is called. a malrotated kidney.

Explanation:

How would the Earth system be different if ice sank in liquid water?

Answers

Answer:

This ice layer insulates the water below it, allowing it to stay liquid, which allows the life within it to survive. If ice sank, the liquid water on top would also freeze and sink, until all the liquid water became frozen. Water is less dense as a solid, than as a liquid, which is why ice floats.

That is the best I got for you!!!

Answer:

If ice sank in liquid water the liquid water on top would also freeze and sink until all the liquid water became frozen. Feel free to correct me if im wrong

HELP PLSSS !!
Based on this data, what can be concluded about the impact
seasonal changes have on these organisms around the Barents Sea?

A. The availability of solar energy limits photosynthetic productivity in winter months

B. Seasonal Changes have no impact on these organisms

C. During winter months the Diatom and zooplankton population completely die off due
to the lack of sunlight.

D. Due to the availability of solar energy, Diatom mass peaks in July.

Answers

Answer:

D. Due to the availability of solar energy, Diatom mass peaks in July.

Explanation:

Diatom are the photosynthetic algae which prepare food for themselves from the solar radiation just like plants. These diatoms produce more biomass or vegetation in the summer season mainly in July because availability of more sunlight in the Barents sea region while on the other hand, less biomass in the winter season due to low temperature and solar radiation which also effects the population of zooplankton organisms. So we can conclude that seasonal changes have a great impact on the organisms living around the Barents Sea.

Answer:

The availability of solar energy limits photosynthetic productivity in winter months

Explanation:

Trust me

5. Which sentence would the author disagree wit

Answers

The author would disagree with C

10. What happens when environments change and species cannot adapt?

Answers

They die out and the ones that adapt will produce offsprings with the same traits to ensure survival

There are ongoing arguments among taxonomists as to which phyla represent the closest relatives of phylum Annelida. Some propose that these worms share a common ancestor with the arthropods (crabs, insects etc.). However, the majority continue to keep the annelids lumped together with the Lophotrochozoa. The reasons for this are many but probably the least disputed comes from:______.
a. the segmented body plan of the annelids.
b. molecular analysis.
c. metamerism.
d. schizocoelous origin of the coelom.

Answers

Answer:

a. the segmented body plan of the annelids

Explanation:

lophotrochozoan is a taxonomy of animals that includes annelids, bryozoans, and brachiopods. This taxonomy of creatures was defined in 1995 as the last ancestor of the taxa of worms, mollusks, and annelids. Their classical definition depends on the topology of the spiral tree of life. Annelids have a segmented body part wherein the external morphological features are repeated in every body segment. It allows the animal to become bigger and makes their movement more fat and efficient.

Answer:

B: Molecular Analysis

Explanation:

I clicked on the other mans answer and was quite dissapointed to see that it was incorrect, so im writting this to tell you its B.

What is the relationship between the places where malaria is common and where the sickle cell allele is commonly found?

Answers

Answer:

At a global scale, the sickle cell gene is most commonly found in areas with historically high levels of malaria, adding geographical support to the hypothesis that the gene, while potentially deadly, avoids disappearing through natural selection by providing protection against malaria.Nov 2, 2010

Explanation:

I hope this helps      :)

Sickle cell anemia is a genetic condition that occurs because of a single point mutation in the DNA gene for hemoglobin. How is this mutation expressed in humans?
A.) The protein coded by the DNA has a different amino acid sequence
B.) The chromosome caring this gene changes shape during cell reproduction
C.) The hormones in the bladder change by increase differences in genes
D.) The carbohydrate code by the DNA has a different structure

Answers

Answer:

B.) The chromosome carrying this gene changes shape during cell reproduction

Explanation:

According to this question, Sickle cell anemia is a genetic condition that occurs when the HBB gene that codes for haemoglobin protein undergoes a point mutation. Mutation alters the genetic sequence of a gene.

This mutation expresses itself when the chromosome 11 carrying the mutated gene changes shape during cell reproduction. Normal Red Blood Cell has a disc-shaped structure, however, this mutation causes a change in shape of the chromosome involved.

In which of the following does the land being moved contain approximately 60% water?
O landslide
slump
O mudflow
creep

Answers

Answer:

Landslide

Explanation:

The blue people of Troublesome Creek Kentucky were genetically isolated from the rest of the world for generations. A rare recessive allele that causes people to have a blue tone to their skin, methemoglobinemia, became disproportionately common within this population by way of their genetic isolation. In the last few decades new roads opened leading to the end of this communities isolation. To the surprise of many, the methemoglobinemia phenotype disappeared along with their genetic isolation. Which of the following may best explain the apparent disappearance of this once common trait?

a. Methemoglobinemia did not confer any physical advantage so that the trait was selected against.
b. Methemoglobinemia was probably lethal and all those that carried this trait died and did not have a chance to pass on this trait to future generations.
c. Those that had the traits simply did not have descendents.
d. With the end of genetic isolation gene flow took place.

Answers

Answer:

The correct answer would be - d. With the end of genetic isolation gene flow took place

Explanation:

It is given that people of Troublesome Creek Kentucky were isolated and have a rare recessive allele that results in a blue tone to their skin. However, later these isolated people connected with the people from outside, and due which allow them to intermate. Intermating among populations from isolated and people from outside leads to gene flow.

Methemoglobinemia was present in the isolated population as they had both recessive alleles in their genotype and other hand people from outside might have heterozygous or both dominant allele genotypes that make them free from this disorder.

Due to the intermating and gene flow, the number of heterozygous conditions rises and after many generations slowly methemoglobinemia could have disappeared due to the masked recessive allele.

How are eukaryotic cell walls different from bacterial cell walls?

Answers

Bacteria cell walls provide structure like plant cell walls. Unlike plant cell walls, however, the bacterial cell wall is responsible only for the one-celled organism itself, without the requirement of connecting and supporting a larger organism composed of many cells

Every year, the tropical rain forest has a rainy season. The forest floor floods, covering once dry areas with water. Some
organisms are unable to tolerate the increased water, so they have to move to other locations to survive.
Which word can best be used to describe this scenario?
(1 point)
O biodiversity
O predation
o disturbance
O damming

Answers

Answer:

it is a disturbance because it drasticly changes the enviroment temeraraly disturbing the animals and forcing them to move

The given scenario can be best illustrated by the term disturbance.

What is disturbance?

Disturbance in ecology refers to a temporary modification in environmental conditions, which makes a pronounced modification within an ecosystem. Disturbances generally act briskly and with great influence, and changes the physical arrangement or composition of abiotic and biotic elements.

The prime ecological disturbances may comprise:

Fires FloodingTramplingInsect outbreaksEarthquakesClimate changeHuman impact

Therefore, in the given scenario, with the increase in the level of water, some of the organisms move to other locations shows that the phenomenon of disturbance has taken place within the ecosystem due to flooding of water.

Thus, the correct answer is disturbance.

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A registered representative at a member firm only deals in stocks and other equity investments. The registered representative helps an associate at that firm negotiate an underwriting of municipal bonds with a municipal issuer official that he knows very well from other business dealings. He does this as a 1-time event and is paid a finder's fee for his help. Which statement is TRUE?a. the registered representative is considered to be a municipal finance professional and is subject to the political contribution rule. b. an "mfp" - a municipal finance professional - is an associated person who solicits business from municipal issuers, renders financial advisory services to municipal issuers, or who performs research or writes reports on municipal issues. c. because the representative was paid a finder's fee for get the municipal underwriting business from the issuer, that registered representative is defined as an mfp and comes under the $250 political contribution limit. What were the European Middle Ages all about ? 3. Compared to the first day of spring, the angle ofinsolation on the first day ofsummer is likely to be1) increase by 15 degrees2) increase by 23.5 degrees3) decrease by 15 degrees4) decrease by 23.5 degrees determine the following I need help with this questionb divided 2 = 4.4 A loss contingency can be accrued when it is certain that funds are available to settle the disputed amount. the amount of the loss can be reasonably estimated and it is probable that an asset has been impaired or a liability has been incurred. it is probable that an asset has been impaired or a liability incurred even though the amount of the loss cannot be reasonably estimated. an asset may have been impaired. what is your GPA score so far don't lie An English instructor asserted that students' test grades are directly proportional to the amount of time spent studying. Lisa studies 4 hr for a particular test and gets a score of 72. At this rate, how many hours would she have had to study to get a score of 96? What is 7/8 divided by 6/13 in the simplest form. Please help me ASAP. insusiri pentru raze calde Discuss the benefits of businesses that are involved in the macro environment The Declaration of Independence stated that all men are created equal- this led to a difference in how people viewed slavery. Which is not true of the statement "All men are created equal"Enslaved people deserved equal rightsAfrican did not deserve the same rights as EuropeansAfricans should not be held in bondage of other men. Of the following, the most important cause of the Great Depression was soaring energy costs soaring energy costs:________ A. serious dislocation in international trade serious dislocation in international trade B. European abandonment of the gold standard European abandonment of the gold standard C. confiscatory social security taxes confiscatory social security taxes D. excessive government spending In which situation would the atoms in an object begin to move closer together during a phase change?Group of answer choicesheat is removed as a gas turns into a liquid.heat is removed as a liquid turns into a gas.heat is added as a liquid turns into a solid.heat is added as a solid turns into a gas. Book Co. is an online book store which sells both fiction and non-fiction books. After analyzing the online book retail industry and assessing its current and predicted sales, Book Co. decides to move away from non-fictions and target only the fiction market which is expected to have a 20% growth in sales. This is an example of __________ strategy. The Rolling Plains ecoregion lies west of the Crosstimbers area of Texas and at elevations between 900-4000 ft. The Rolling Plains is a part of the central United States Great Plains system. Like the Crosstimbers ecoregion, it has rolling hills. These topographical features are due to the several rivers that flow through this ecoregion. The rivers in the area weather and erode the land, forming __________ in this area. what you think of yourself is much more important than what other people think of you what does it mean??? A storage shed is a rectangular prism and has dimensions of 6 meters by 5 meters by 12 meters. If Jean were to double these dimensions, she believes she would only double the volume. Is she correct? Explain why or why not. Include a drawing in your explanation. Find a linear equation to solve for the following unknown quantities: One number is three more than twice another number. If the sum of the two numbers is 36, what are the numbers?