If proteins do not have the correct structure, they cannot function properly. Protein misfolding is a cellular malfunction that occurs when proteins do not properly get modified and folded into their correct 3D shape after they are initially synthesized.
Which of these cell structures is most likely responsible for protein misfolding?

NUCLEOUS
LYSOSOME
ENDOPLASMIC RETICULUM
MITOCHONDRIA

Answers

Answer 1

Answer:

The correct answer is - ENDOPLASMIC RETICULUM

Explanation:

In the cell, all cell organelle performs a specific function. Protein synthesizes with the help of ribosomes then they are sent to the endoplasmic reticulum for folding the proteins to their correct form or shape before sending them to the Golgi body for packaging.

Protein folding is an important function performed by the ER and must be correctly folded into particular 3-D shapes in order to function correctly and if not correctly folded then degraded by lysosomes.


Related Questions

why are animals cells important for survival?
The answer in a paragraph!!

Answers

Answer:

If there are no animal cells, then life on earth would not exist. Also plants would dominate.

Explanation:

In a population of birds, the average beak size is favored. What type of selection is this?
a. directional
b. disruptive
c. tabilizing
d. kin

Answers

Answer:

C. Stabilizing selection

Explanation:

Natural selection, is of three different types namely: disruptive selection, directional selection and stabilizing selection. Disruptive selection occurs when the two extremes of a population are being favored over the average or intermediate.

Directional occurs when one extreme of a population is favored. However, in STABILIZING SELECTION, the average or intermediate population is favored over both extremes of a population. Example is when the average-sized beaks of a bird population is being favored over the long and short ones (extremes).

Answer:

the answer is stabilizing.

Explanation:

I got it right on my test.

does anyone a\have any tips for caring for aloe and/or rose moss? i just got starter kits but i havent really cared for plants before, ty

Answers

I know they need lots of sunlight, but it can get sunburnt so be careful. They need to be watered around 3 times a day. Sorry if this isn't what you were looking for!

The _____ says that in a series of sedimentary rock layers, the younger rocks are normally on top of the much older rocks.
A) rock theory
B) fossil record
C) law of superposition
D) index fossil

Answers

The answer is B GOOD LUCK

Answer:

C

Explanation:

The law of superposition says that in a series of sedimentary rock layers, the younger rocks are normally on top of the much older rocks.

How does coastal erosion shape Florida?

PLS ANSWER ASAP

Coastal erosion causes the sea level to rise.
Coastal erosion causes the beach to wear away.
Coastal erosion causes sand to move with longshore currents.
Coastal erosion causes the formation of sinkholes in the ground.

Answers

Answer: B costal erosion causes the beach to wear away

Who was first reported lysosome??? and also in which year​

Answers

Answer:

Christian De Duve in 1955 discovered the lysosome. He started studying lysosomes in 1949 & finally discovered them in 1955.

A wrinkled, green seed and a round yellow seed were grown into plants and mated. In the F1 generation, half the seeds were round and yellow; the other half were round and green. The round yellow seeds were grown into plants and allowed to self-fertilize. In the F2 generation, what fraction of the seeds will be genotypically identical to the plants of the parental generation

Answers

Answer:

Parental generation:        rr yy           and     RR Yy

                                wrinkled, green         round, yellow

F2) 2/16 RRYy

      1/16 rryy                          

Explanation:

Due to technical problems, you will find the complete answer and explanation in the attached files

Scientists looking for a repressor of the androgen receptor (AR)-mediated transcription gene discovered a protein, Ankrd1. ARs were observed to bind to Ankrd1 and, in cells where Ankrd1 was over-expressed, AR-mediated transcription was inhibited. The scientists also detected lower levels of ARs when Ankrd1 was overexpressed using chromatin immunoprecipitation (ChIP) and Ankrd1 was not detected by ChIP.Based on these observations, which of the following conclusions would the scientists most likely draw?
A. Ankrd1 is binding to ARs and preventing ARs from binding to the promoter, which inhibits mRNA transcription
B. Ankrd1 is binding to the promoter and blocking ARS from binding, which prevents transcription of AR- mediated genes.
C. Ankrd1 is binding to multiple sites and causing DNA to loop, preventing ARS from binding and activating gene transcription
D. Ankrd 1 is binding to chromatin, recruiting proteins that remove acetyl groups, and silencing transcription of that region of DNA.

Answers

Answer:

D. Ankrd 1 is binding to chromatin, recruiting proteins that remove acetyl groups, and silencing transcription of that region of DNA.

Explanation:

Ankrd is a binding chromatin, there is recognition that mutation is deregulating the chromatins. The proteins remove acetyl groups and then the region for DNA transcript. The recruitment chromatin is associated with proteins are enzymes which are chemical moieties.

Answer:

Ankrd1 is binding to ARs and preventing ARs from binding to the promoter, which inhibits mRNA transcription

Explanation:

Just took the test :)

Evolution shows us that all living organisms have a

Answers

Answer:

cell membrane, nucleus, nucleolus, nuclear membrane, cytoplasm, endoplasmic reticulum, Golgi apparatus, ribosomes, mitochondria, centrioles, cytoskeleton, vacuoles, and vesicles.

Explanation:

Cytokinesis in animal cells happens when the:
A: cell wall pinches in to separate the cytoplasm.
B: cell plate forms across the middle of the cell.
C: chromosomes line up in the middle of the cell.
D: cell membrane pinches in to separate the cytoplasm.

Answers

Answer: D

Explanation:

Cytokinesis is basically the formation of 2 new  cells. C describes metaphase and A and B are talking about cytokinesis in a plant cell because animals don't have cell walls or plates. So the right answer has to be D

PLZ answer fast will give brainliest!!! Even if you can only answer one of the questions it would be appreciated.

a) Describe the differences between the R groups of the amino acids located in the transmembrane domains and those located in the amino- or carboxy-terminus of TRPV1. Describe the specific location in the cell where TRPV1 protein is synthesized.

(b) The pGoG protein leads to the inhibition of cyclin activity. Explain how this interferes with cell cycle progression.

(c) Researchers discover a mutation that prevents NFAT2 from being phosphorylated. Predict the effect of this mutation on apoptosis by the pathway shown in Figure 2. Provide reasoning to justify your prediction.

(d) The drug cyclosporin A is known to inhibit calcineurin. Researchers claim that cyclosporin A should not be given to patients with cancer. Support the researchers' claim based on the pathway shown in Figure 2.

Answers

Answer:

The perception of pain throughout the body arises when neural signals originating from the terminals of nociceptors are propagated to second-order neurons in the spinal cord or brainstem, whereupon they are transmitted to specific higher-order brain areas (Price, 2000). Recent studies have begun to elucidate some of the molecular mechanisms underlying the transduction of noxious stimuli. Many stimuli have been found to activate ion channels present on nociceptor terminals that act as molecular transducers to depolarize these neurons, thereby setting off nociceptive impulses along the pain pathways (Price, 2000; Costigan and Woolf, 2000). Among these ion channels are the members of the transient receptor potential (TRP) family. To date, the most studied member of the TRP family is the TRPV1 receptor. This is because it is the only one activated by capsaicin, the compound in chili pepper responsible for its “hot” taste; also, inhibiting TRPV1 has been shown to have therapeutic value (DiMarzo et al., 2002; Cortright and Szallasi, 2004). Although we will focus on the presence of these channels in nociceptors, we note that they have been identified in many other cell types and in various cortical and subcortical areas (Toth et al., 2005).  The transient receptor potential vanilloid 1 (TRPV1) channel is predicted to have six transmembrane domains and a short, pore-forming hydrophobic stretch between the fifth and sixth transmembrane domains (see Figure 5.1A). It is activated not only by the vanilloid capsaicin (Caterina et al., 1997), but also by noxious heat (>43°C) and low pH (Caterina et al., 1997; Tominaga et al., 1998), voltage (Gunthorpe et al., 2000; Piper et al., 1999), and various lipids (Julius and Basbaum, 2001; Caterina and Julius, 2001; Clapham, 2003; Cortright and Szallasi, 2004, Szallasi and Blumberg, 1999; Prescott and Julius, 2003; Jung et al., 2004; Bhave et al., 2003). In cells, TRPV1 is inactivated by its binding to PIP2 and is released from this block by PLC-mediated PIP2 hydrolysis (Prescott and Julius, 2003). TRPV1 is widely expressed in central nervous system (CNS) tissue and highly expressed in sensory neurons of the dorsal root ganglion [19]. This receptor also localizes to neurons that line the oral and nasal cavities [10], where it is found in a subpopulation of sensory afferent nociceptive nerve fibers [20].

(this is for question 1.)

Explanation:

Answer:

see explanation :)

Explanation:

a) R groups in the transmembrane domain should be hydrophobic while R groups in either terminus should be hydrophilic, and the TRPV 1 protein is synthesized on the ribosomes attached to the rough endoplasmic reticulum.

b) Cyclins cannot activate cyclin-dependent kinases which normally phosphorylate other proteins to move the cell through a cell cycle checkpoint.

c) Apoptosis will be induced and if NFAT2 cannot be phosphorylated, it will be able to inhibit ATF3 expression, which which enables activity of  pGoG  which will induce apoptosis.

d) If Calcineurin is inhibited, then the steps in this pathway that follow from calcineurin activation will be unable to block cell division/induce apoptosis. Since cancer is characterized by excessive cell division, this drug would be an inappropriate treatment for cancer.

Which of the following describes why phospholipids are better suited to forming the cell membrane than regular fats or steroids? A:Their glycerol head allows them to bond easily with most other molecules. B: Their phosphate group gives them a hydrophilic end. C: Their three-pronged structure allows them to store large amounts of energy. D: Their unique ringed structure provides them with the ability to regulate cell metabolism.

Answers

Answer:

B

Explanation:

Answer:

Their phosphate group gives them a hydrophillic end.

Explanation:

I got it right on the test.

Grafting produces a plant that is a clone of the rootstock.
O True
O False

Answers

Answer:

The answer is True.

4. What is the difference between a Nucleolus and a Nucleoid?

Answers

The nucleus is the largest and the most important cell organelle in a eukaryotic cell. A nucleus is a membrane-bound organelle that houses the genetic material of eukaryotes in DNA. The nucleus consists of protein fibres or the DNA inside chromatin fibres. Nucleoids contain the genetic material of prokaryotes in the cytoplasm. The nucleoids usually consist of a single chromosome.

Let us look at more difference between nucleus and nucleoid in the table given below.

Answer: It has different letters.

Explanation: Nucle = prefix.

Olus in Nucleous and Oid in Nucleoid

when a single cell of E. coli reproduces it first duplicates it's dna next the cell elongates as each copy of dna is pulled toward opposite ends of the cell the membrane then pinches inward, dividing the cytoplasm into two halves and producing two daughter cells what is true about these daughter cells​

Answers

Answer:

They are identical

Answer:

They are genetically identical to the parent because they are produced by asexual reproduction.

Hope this helps!

Explanation:

What is the correct sequence of events that occur during protein synthesis?

1.mRNA is formed
2.amino acids form polypeptides.
3.a strand of dna segment unwinds.
4.mRNA attaches to ribosomes.
5.tRNA supplies the required amino acids.

Answers

Answer:

3, 1, 4, 5, 2

Explanation:

DNA helicase enzyme will unwind DNA into 2 segments for a template. Complementary nitrogenous bases will attach themselves to one of the DNA strands. mRNA carries codons for instructions from DNA. mRNA leaves the nucleus and joins with a ribosome (tRNA) in the cytoplasm. tRNA has anticodons which are complementary to a specific mRNA molecule. tRNA pairs with and translates instructions that the mRNA is carrying. Each amino acid delivered to the ribosome by tRNA begins forming a chain of amino acids, called a peptide bond.

PLEASE HELP
Daylight Savings Time has pros and cons. Do you think the pros outweigh the cons and therefore Daylight Savings Time should continue? Instead, do you think the cons outweigh the pros and therefore Daylight Savings Time should be abolished?

Explain.

Answers

Answer:

It should be abolished

Explanation:

It doesn't help anyone. The idea is that people will use less resources but because some people sleep throughout the day and work at night (especially now that we are at home). Its counter intuitive,  it used to work but not everything that works for the past,  works for the future.

Page No
Date
What is Science?​

Answers

the intellectual and practical activity encompassing the systematic study of the structure and behaviour of the physical and natural world through observation and experiment.

HELP ME ASAP



read the article above and answer the questions below :



1. The part of digestive system that breaks down food with acid is the

A. Teeth

B. Stomach

C. Small intestine

D. Rectum



2. The part of the digestive system where the nutrients in food are absorbed is the

A. Teeth

B. Stomach

C. Small intestine

D. Rectum



3. The processed food that the stomach sends to the intestines is called

A. Chyme

B. Duodenum

C. Both a. and b. above

D. None of the above



4. The most digestion takes place in the

A. Stomach

B. Duodenum

C. Rectum

D. None of the above



5. The food you eat becomes fuel for your

A. Brain

B. Muscles

C. Both a. and b. above

D. None of the above



6. The proteins, carbohydrates, and fats from the food that was eaten travels to cells throughout the body in the

A. Stomach

B. Duodenum

C. Small intestine

D. Blood

Answers

1. B Stomach
2. C Small intestine
3. A Chyme
4. D None of the Above
5. C Both A and B
6. D Blood

If a mRNA strand was as follows: UACCAGUUGCGA, how many codons
does it have?
a. one
b. three
c. twelve
d. four

Answers

Answer:

Option B) three

I hope this might help u

The Punnett square is used to

A determine the probability of offspring traits.

B determine the parent alleles of the offspring.

C determine the location of mutated genes.

D determine the makeup of chromosomes.

Answers

a) determine the probability of offsprings traits

If Dr. Jensen has type A blood, what antigens does she have on her red blood cells (RBC)?​

Answers

Mhmm I really don’t know I’m just tryna get some points

How do I solve for this

Answers

Answer:

where

Explanation:

Answer:

solve for what

Explanation:

there is nothing attached

Combining your knowledge of rates of diffusion with your knowledge of muscle physiology, explain why it is advantageous for oxidative muscle fibers (which depend on aerobic metabolism to generate ATP) to have smaller diameters compared to glycolytic muscle fibers.

Answers

Answer:

To provide quick energy to the muscles.

Explanation:

It is advantageous for oxidative muscle fibers to have smaller diameters compared to glycolytic muscle fibers because these fibers depend on aerobic respiration to provide energy to muscle contractions. This smaller diameter enables the oxidative muscle fiber to move very quickly in order to provide quick energy to the muscles. If their diameters are big so they are unable to provide quick energy in the form of ATP to the muscles for their contractions.

After visiting a factory on a field trip, your little sister is really concerned about her carbon footprint. Name two ways that she can reduce her carbon footprint at home. please help ​

Answers

Just don’t walk. Sorry it wasn’t let me ask anymore questions unless I answer one

importance of cycle events​

Answers

Explanation:

sorry for the handwriting

What does "plate margin" mean?

Answers

Answer:

plate margin (plate boundary) The boundary of one of the plates that form the upper layer (the lithosphere) and together cover the surface of the Earth. Plate margins are characterized by a combination of tectonic and topographic features: oceanic ridges, Benioff zones, young fold mountains, and transform faults.

Plate margins are plates that form the lithosphere. Plate margins are things like oceanic ridges and mountains. Basically just a plate that makes up different types of land.

Select a region of the world and explain how its latitude, elevation, geographical
features, and relationship to winds and ocean currents determine its climate.

Answers

Answer:

Do you have an attachment to add?

I dont see a map :(

Explanation:

What characteristic can all organisms in the Kingdom Fungi can be described by

Answers

Answer:

Eukaryotic

Explanation:

Fungi are eukaryotic, non-vascular, non-motile and heterotrophic organisms. They may be unicellular or filamentous. They reproduce by means of spores. Fungi exhibit the phenomenon of alternation of generation.

Which nacromolecules found within cells do not dissolve in water?
A. O carbohydrates
B. O nucleic acids
C. O proteins
D. O lipids

Answers

D. Lipids would be your answer
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