The mitochondria of eukaryotic cells contain two forms of the EF G protein. EF G1mt acts an elongation factor as expected, but EF G2mt acts as a ribosome recycling factor. Individuals with certain single nucleotide polymorphisms (SNPs) in the EF G2mt gene are known to have an increased number of side effects associated with taking statin drugs that treat high cholesterol. The most common side effect is muscle weakness, but they can be as severe as muscle breakdown and liver failure. Propose a mechanism by which SNPs in the EF G2mt gene may lead to these side effects.

Answers

Answer 1

Answer:

The correct answer is - polymorphism mechanism.

Explanation:

Polymorphism mechanism in mitochondrial elongation factor gene EFG2: It involves escalates the atorvastatin toxicity and affects the cell respiratory function. Polymorphisms within the EFG2 factor gene lead to the implication in disease. This gene factor may result in adverse drug reactions such as STATIN, that can leads to side effect to the condition that can affect skeletal muscle severely.

EFG2 plays an essential role which is specific in mitochondrial ribosome recycling. EFG2mt gene is required for cell growth on galactose medium using small interfering RNA splicing of expression in human cell lines.

Such mutation exhibits an atorvastatin-sensitive phenotype and shows less respiratory capacity. this concludes that the first phenotype associated with SNPs in the EFG2mt gene and implicates the human EFG2mt gene as a pharmacogenetic gene for stain toxicity in humans.


Related Questions

Which two body systems?? Let me know

Answers

Answer:

They are the digestive and the respiratory systems (O2 as nutrient and CO2 as waste)

Answer:

Most likely Excretory and Digestive

Does your conclusion support or reject your hypothesis?​

Answers

Your conclusion should only support your hypothesis if your hypothesis is correct if not in the conclusion put what was actually the awnser and how it compared to your hypothesis

Suggest three reasons why the percentages are so much higher in Sub-Saharan Africa.

Answers

Answer:

education on HIV / AIDS less effective;

sexual attitudes / number of partners ;

availability of condoms ;

poverty / poorer / less money ;

sex industry ;

less primary health care / less likely to be diagnosed

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Which of these phylogenetic trees depicts a different evolutionary history than the others?









A. Tree 1
B Tree 2
C tree 3
D tree 4

Answers

I would say tree 3 because it just looks different overall

Tree 3 depicts a different evolutionary history than the others. So, the correct option is C.

What is Phylogenetic relationship?

A phylogenetic tree is defined as a branching diagram or a tree that shows the evolutionary relationships between different biological species or other entities based on similarities and differences in their physical or genetic characteristics. All life on Earth is part of a single phylogenetic tree that points to common ancestry.

These relationships are identified by using the similarities in DNA, RNA, or protein sequences, or by comparing the anatomical features. Through this, we get to know that all life arises from a common ancestor. In the above given information, Tree 3 shows the phylogenetic relationship.

Thus, Tree 3 depicts a different evolutionary history than the others. So, the correct option is C.

Learn more about Phylogenetic relationship, here:

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Parent strand of DNA is CCTAGCT. What is the complementary strand?

Answers

Answer:

GGATCGA

Explanation:

Adenine goes with thymine and Cytosine e goes with guanine.

Basically A is with T; C is with G

Note that:

C matches with G

T matches with A

In this case, the strand of DNA given is CCTAGCT. The complementary strand would therefore be GGATCGA.

~

**Brainiest if correct**
Write 5-6 sentences about snakes. (This is for an informational paper, make if formal!) Please don't put links/files to download because I can't download on this computer since it is the family computer. THANK YOU!

Answers

Snakes can live up to 9 years. They slither up to 18 mph. Snakes are reptiles that are elongated, limbless, and carnivorous. Another interesting thing about snakes is that they don’t have eyelids. The last fact is that snakes can open there mouths up to 150 degrees so they can swallow there prey.

explain what is crossing-over in your own words

Answers

Explanation:

it occurs during meiosis. Its the exchange of chromosome pieces between the non-sister chromatids during the production of gametes.

Answer:

Crossing-Over is a DNA segment on each chromosome section may code for eye color, although one chromosome may code for brown eyes and the other for blue eyes. Crossing over occurs most often between different alleles coding for the same gene.

Explanation:

25. Drumlins, kettle lakes, and erratics are features of which agent of
erosion?

-glacial ice
-winds
-running water
-ocean waves

Answers

Answer:

running water

Explanation:

Which of the following is NOT true of plants?
A. They have cell walls of cellulose
B. most of them are multicellular.
C. they are autotrophic/photosynthetic
D. they are heterotrophic

Answers

I think it’s B as well

When both alleles are the same the individual is what for that trait

Answers

Answer:

heterozygous

Explanation:

i can't paste the explanation here because it restricts me for some reason

hope this answered your question and have a good day

Reactions that consume CO2 take place in?

Answers

Answer:

The Stroma of the chloroplast.

Explanation:

This answer is correct

An example elements nutrients faculative nutients in tissue plants N and Fe:
a. False
O b. True

Answers

the answer might be true

Hummingbirds share a mutualistic relationship with the flowers they feed on. Which of
these statements about the relationship between the flower and the hummingbird is true?

Answers

Answer:

yes

Explanation:

how long until blowfly maggots hatch on a dead body

Answers

Answer:

c

Explanation:

The Przewalski’s horse became endangered during the middle of the last century when the species experienced a population bottleneck, the result of human activity. Loss of habitat and human’s hunting them for food. What is a consequence of this type of genetic drift.

A.
Use and disuse

B.
Acquired variation

C.
Increase of genetic diversity

D.
Decrease of genetic diversity

Answers

I think it’s D
Hope this helps

Which of the following best describes the principle of independent
assortment?

Answers

Answer:

Law that states that the segregation of any pair of alleles is independent of any other pair of alleles . As a result each pair of gametes receives one member of every pair of alleles.no influences from other alleles is necessary.

Explanation:

Can you help me put them in the right please asap I will mark brainly

Answers

Evaporation & transpiration, condensation, precipitation, infiltration, ground water. If there’s run off also it goes before infiltration

A DNA base sequence of ACAGTGC would code for​

Answers

Answer:

TGTCACG

Explanation:

Using Chargaff's rule:

A=T

G=C

It can give you the complimentary strand.

For the situation below , determine whether the premium will likely increase , decrease, or remain the same. Jamie just turned 25

Answers

Answer:

The premium decreases when Jamie turns 25 years old.

Explanation:

The question above is about auto insurance premiums, which, as the name already says, is insurance aimed at automobiles, with the objective of promoting economic and financial protection in relation to accidents and problems that may happen in these vehicles.

When an individual turns 25, like Jamie, the insurance premium decreases in value, that is, the insurance companies offered cheaper and more economical rates to the driver when he is going to renew the contract.

GUYS GUYS PLEASE ANSWER QUICK HELP!!!! 20 points!!!

Answers

Answer:

1

Explanation:

if their feeding overlaps in fall and not summer than 1 is the answer

hi how long does it take for mitosis to complete? why will most of the cells you view be in interphase?

Answers

it will take two hours and Interphase is the phase of the cell cycle in which a typical cell spends most of its life. Interphase is the 'daily living' or metabolic phase of the cell
Usually, cells will take between 5 and 6 hours to complete S phase. G2 is shorter, lasting only 3 to 4 hours in most cells. In sum, then, interphase generally takes between 18 and 20 hours. Mitosis, during which the cell makes preparations for and completes cell division only takes about 2 hours.

Why is it a good thing to have a lot of genetic variation within a population or species?
Group of answer choices

A. If conditions change, you have a greater chance of someone having adapatations that allow them to survive and reproduce.

B. You will produce the most attractive offspring.

C. You will produce the most offspring.

Answers

Answer:

A. If conditions change, you have a greater chance of someone having adaptations that allow them to survive and reproduce.

I think the answer would be b hope it helps

what are the diseases of defective receptor function​

Answers

Thyroid disease , effects the receptors of thyroid hormones

true or false?: If a Father has a dominant X linked trait then ALL
offspring will be affected

Answers

Answer:

true

Explanation:

Answer:

true ㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤㅤ

Okazaki fragments are formed on which strand?

Answers

Answer:

The leading strand is continuously synthesized and is elongated during this process to expose the template that is used for the lagging strand (Okazaki fragments). During the process of DNA replication, DNA and RNA primers are removed from the lagging strand of DNA to allow Okazaki fragments to bind to.

Explanation:

Hope it helps

Explain the process of cell division

Answers

Explanation:

TO veiw the answer open the file

b) The frequency of allele A, is 0.3 or 30%. Does this mean that 30% of the individuals in the
population will have an A, phenotype? (1 point)

Answers

Answer:

no because 0,3 is 3/10 and not 30$

Explain how organisms contribute to the
creation of soil.

Answers

When organisms die they release the nutrients back to the soil

Explanation:

Soil formation is influenced by organisms (such as plants), micro-organisms (such as bacteria or fungi), burrowing insects, animals and humans.

As soil forms, plants begin to grow in it. The plants mature, die and new ones take their place. Their leaves and roots are added to the soil. Animals eat plants and their wastes and eventually their bodies are added to the soil.

This begins to change the soil. Bacteria, fungi, worms and other burrowers break down plant litter and animal wastes and remains, to eventually become organic matter.

I need help with this question

Answers

Answer:

It is Nervous and Muscular

Explanation:

3. Suppose two animals live in the same loca-
tion and eat the same kind of food. What
adaptation would decrease the competition
between them?

Answers

Answer:

One eats during the day and the other eats at night.

Explanation:

Answer:

Well, it really depends on the type of animal (for example water, land). However an adaptation like being able to eat different foods would decrease competition between them as they don't have to hunt the same prey.

Explanation:

I don't really know how to explain this. Sorry if my answer is bad.

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