You have 16 rare diploid yeast strains with which you want to perform this analysis. You put the two oligos (ASO#1 and ASO#2) on membranes (ASO#1 on the top row and ASO#2 on the bottom). You then extract genomic DNA from the yeast and PCR-amplify the DNA using primers that flank the AWA1 gene’s coding region. You label the PCR products with radioactivity and treat them chemically to make them single-stranded. You allow the labeled DNA to hybridize to the oligos, and you wash away any unbound DNA.
Predict the results for: strain 1 (homozygous for functional AWA1), strain 2 (heterozygous for functional AWA1 and awa1) and strain 3 (homozygous for awa1) by shading in the regions where you should see a hybridization signal below.

Answers

Answer 1

The analysis provided in the question uses a diploid yeast and involves a PCR-amplification of DNA.

Once the DNA is PCR-amplified, radioactivity is used to label the PCR products and treated chemically to make them single-stranded.

Subsequently, the labeled DNA is allowed to hybridize to the oligos, and any unbound DNA is washed away.

Homozygous for functional AWA1

In strain 1, which is homozygous for the functional AWA1 gene, it is expected that a hybridization signal will be present in the first row where the ASO#1 oligo is located, but not in the second row where ASO#2 is located.

you should see a hybridization signal in the top row of the membrane and no signal in the bottom row.

Heterozygous for functional AWA1 and awa1

For strain 2, which is heterozygous for functional AWA1 and awa1, hybridization signals should be visible in both rows of the membrane.


Homozygous for awa1

you should see a hybridization signal in the bottom row of the membrane and no signal in the top row.

To know more about involves visit:

https://brainly.com/question/22437948

#SPJ11


Related Questions

What are enantiomers? Choose the most accurate response. a. molecules that have different molecular formulas but same structures b. substances with the same arrangement of covalent bonds, but the order in which the atoms are arranged in space is different c. molecules that are mirror images of each other and that cannot be superimposed on each other d. groups of atoms covalently bonded to a carbon backbone that give properties different from a C-H bond You and your close friend have isolated a novel bacterium from the Sargasso Sea and cloned its pyruvate kinase gene. You want to test whether it can really catalyze the very last reaction of glycolysis which is a substrate phosphorylation reaction. You must provide which of the following substrates to test your idea, in addition to ADP and other components? a. phosphoenol-pyruvate b. glucose 6-phosphate c. glyceraldehyde 3-phosphate d. lactate e. ethanol

Answers

Enantiomers are molecules that are mirror images of each other and cannot be superimposed on each other. This is the most accurate response.

The correct answer is phosphoenol-pyruvate.Enantiomers are molecules that have the same composition but differ in their spatial arrangement of atoms. Enantiomers are mirror images of each other, similar to left and right hands, and have the same physical and chemical properties except for their optical activity (rotation of plane-polarized light).

Enantiomers also have identical molecular formulas and structural formulas. Hence, the correct answer is c. substances with the same arrangement of covalent bonds, but the order in which the atoms are arranged in space is different.

To know more about molecules visit:

https://brainly.com/question/32298217

#SPJ11

if tetanus tocoid is tje antigen and it produced IgG in vaccination, what is it considered?
a. polysaccharide
b. chemotaxin
c. it is a protein
d. anaphylatoxin

Answers

The tetanus toxoid, which produces IgG in vaccination, is considered a protein. The correct answer is c. It is a protein, referring to the tetanus toxoid antigen.

tetanus toxoid IgG (Immunoglobulin G) is a type of antibody produced by the immune system in response to an antigen. In this case, the antigen is the tetanus toxoid, which is a modified form of the tetanus toxin. The tetanus toxoid is a protein-based antigen, DNA vaccine and when it is introduced into the body through vaccination, it stimulates the production of IgG antibodies.

Polysaccharides are carbohydrates composed of multiple sugar molecules linked together, and they are not applicable in this context. Chemotaxins are substances that attract immune cells to a specific site, which is not relevant to the question. Anaphylatoxins are complement proteins involved in triggering allergic reactions, and they are not related to the production of IgG antibodies.

Learn more about DNA vaccine here

https://brainly.com/question/29569196

#SPJ11

Which of the following medical conditions are considered to be
disorders of the nervous system? Select all that apply.
1. Multiple sclerosis
2. Pericarditis
3. Cholecysitis
4. Epilepsy
5. Aphasia

Answers

Medical conditions that are considered disorders of the nervous system are multiple sclerosis, epilepsy and aphasia.

Here is a more elaborate answer on each of these conditions:

Multiple sclerosis (MS) is a demyelinating and degenerative disorder of the central nervous system. MS is a chronic and usually progressive disease that affects the myelin sheaths that surround the nerve fibers, causing a range of neurological symptoms. This disorder can affect any part of the central nervous system (CNS), including the brain, spinal cord, and optic nerves, but the most common site is the optic nerve. Some common symptoms of MS include vision problems, muscle weakness and stiffness, speech and swallowing difficulties, chronic pain, and fatigue.

Epilepsy is a group of neurological disorders characterized by seizures that can be triggered by various factors, such as a high fever, head injury, or drug use. The seizures are caused by abnormal electrical activity in the brain. Epilepsy can be a chronic condition that requires lifelong treatment, and the frequency and severity of seizures vary widely from person to person. Common symptoms of epilepsy include seizures, confusion, loss of consciousness, and muscle stiffness.

Aphasia is a communication disorder that is caused by damage to the language areas of the brain. It can affect a person's ability to speak, understand, read, and write. The severity of the disorder can vary widely, ranging from mild to severe. Some people with aphasia may have difficulty finding words or forming sentences, while others may be unable to speak at all. Aphasia can occur as a result of a stroke, head injury, or other medical conditions, such as brain tumors or infections. There are several types of aphasia, including expressive aphasia, receptive aphasia, and global aphasia.

To know more about nervous system disorders visit:

https://brainly.com/question/30587203

#SPJ11

Acetyl-CoA is an important intermediate that participates (either as an input, an output, or an intermediate) in all of the below processes EXCEPT O Photorespiration O the Citric Acid Cycle B-oxidation cycle Acetyl-CoA participates in all these processes O Glyoxylate cycle Determination of an enzyme or pathway Q10 provides information on O a method to compare two alternative enzymes or pathways at a single temperature O gas solubility in response to temperature O the relative thermal motivation of a biochemical pathway a O the temperature sensitivity of an enzyme or pathway O the temperature switch point between C3 and CAM photosynthesis

Answers

Acetyl-CoA is an important intermediate that participates in all of the processes mentioned except gas solubility in response to temperature.

Option (F) is correct.

Acetyl-CoA is a central molecule in cellular metabolism. It is involved in various biochemical processes, including the ones mentioned:

A) Photorespiration: Acetyl-CoA participates in photorespiration as an input in the glycolate pathway, which helps plants recover carbon during inefficient photosynthesis.

B) The Citric Acid Cycle: Acetyl-CoA enters the citric acid cycle, also known as the Krebs cycle, where it undergoes a series of reactions to generate energy-rich molecules such as ATP.

C) β-oxidation cycle: Acetyl-CoA is produced as an output during the breakdown of fatty acids in the β-oxidation cycle, which occurs in mitochondria.

D) Glyoxylate cycle: Acetyl-CoA serves as an intermediate in the glyoxylate cycle, allowing certain microorganisms and plants to convert acetyl-CoA into carbohydrates.

E) Determination of an enzyme or pathway Q10: Acetyl-CoA can participate in the determination of the temperature sensitivity of an enzyme or pathway using the Q10 value, which describes the rate of change with temperature.

However, F) Gas solubility in response to temperature does not involve Acetyl-CoA directly. It refers to the solubility of gases, such as oxygen or carbon dioxide, in liquids and is influenced by factors like temperature and pressure.

To learn more about Acetyl-CoA  here

https://brainly.com/question/16000193

#SPJ4

Complete question is:

Acetyl-CoA is an important intermediate that participates (either as an input, an output, or an intermediate) in all of the below processes EXCEPT:

A) Photorespiration

B) The Citric Acid Cycle

C) β-oxidation cycle

D) Glyoxylate cycle

E) Determination of an enzyme or pathway Q10 provides information on

F) Gas solubility in response to temperature

G) The relative thermal motivation of a biochemical pathway

H) The temperature sensitivity of an enzyme or pathway

I) The temperature switch point between C3 and CAM photosynthesis

2. Enterobius vermicularis is infective in___ form and causes ____
a. larval; pinworm
b. egg; hookworm
c. egg; pinworm d.larval; hookworm 3. The reproductive structure of Taenia is a a.hook b.proglottid c. scolex d.heterocyst
4. Trichinella spiralis is transmitted by
a. ingestion of a cyst b. ingestion of a larva
c. ingestion of an egg d.a vector 5. Which type of sample would be used to aid in diagnosis of a Clonorchis infection? a. Fecal smear b.Sputum sample
c. Skin scraping d.Blood sample

Answers

Enterobius vermicularis is infective in the egg form and causes pinworm infection. The reproductive structure of Taenia is the proglottid. Trichinella spiralis is transmitted by ingestion of a larva. A fecal smear would be used to aid in the diagnosis of a Clonorchis infection.

Enterobius vermicularis is infective in the egg form and causes pinworm infection. The eggs of Enterobius vermicularis are ingested, usually through contaminated food, water, or by direct contact with infected individuals. Once inside the body, the eggs hatch in the small intestine, and the larvae migrate to the large intestine, where they mature into adult worms. The adult female worms then migrate to the perianal area to lay their eggs, leading to itching and discomfort.

The reproductive structure of Taenia, a genus of parasitic tapeworms, is the proglottid. Proglottids are segments that make up the body of a tapeworm and contain both male and female reproductive organs. Each proglottid is capable of producing eggs, which are then released into the environment through the feces of the infected host. The proglottids can detach from the tapeworm's body and be passed in the feces, enabling the tapeworm to spread and infect new hosts.

Trichinella spiralis, a parasitic roundworm, is transmitted by the ingestion of a larva. The larvae of Trichinella are encysted in the muscle tissue of infected animals, typically pigs or other mammals. When these infected meat products are consumed by humans, the larvae are released in the digestive system, where they mature into adult worms. The female worms then produce larvae that migrate to muscle tissue, causing a condition known as trichinellosis.

To aid in the diagnosis of a Clonorchis infection, a fecal smear would be used. Clonorchis sinensis is a parasitic liver fluke that infects humans through the consumption of raw or undercooked freshwater fish containing the infectious larvae. The adult flukes reside in the bile ducts of the liver. The presence of Clonorchis eggs in a fecal smear can indicate an infection, as the adult flukes release eggs into the feces. Other diagnostic methods may include serological tests or imaging techniques to visualize the flukes in the bile ducts.

Know more about Trichinella spiralis here:

https://brainly.com/question/30978492

#SPJ11

Which one is the correct hierarchical sequence of the auditory stimulus processing? (Some intermediate structures may be omitted.)
a) Vesibulocochlear nerve - Inferior Colliculus - Cochlear Nuclei - Medial Geniculate nucleus - Primary Auditory cortex.
b) Cranial nerve VIII - Cochlear Nuclei – Medial Geniculate nucleus - Inferior Colliculus - Primary Auditory cortex.
c) Cranial nerve V - Cochlear Nuclei – Inferior Colliculus - Medial Geniculate nucleus - Primary Auditory cortex.
d) Hair cells – Spiral ganglion cells – Cochlear Nuclei – Inferior Colliculus - Medial Geniculate nucleus - Primary Auditory cortex.

Answers

The correct hierarchical sequence of the auditory stimulus processing is (b) Cranial nerve VIII - Cochlear Nuclei – Medial Geniculate nucleus - Inferior Colliculus - Primary Auditory cortex. Here is an explanation for each of the structures:

Auditory stimulus processing is the step-by-step process that sound waves undergo as they travel from the ear to the brain for interpretation. The structures involved in this process are as follows:

Cranial nerve VIII (CN VIII) or Vestibulocochlear nerve: This is the nerve responsible for transmitting sound information from the ear to the brain.

Cochlear Nuclei: These are two small clusters of cells located in the brainstem. They receive and process sound information from the cochlea.

Medial Geniculate Nucleus: This is a group of nuclei in the thalamus that act as the main relay center for auditory information processing.

Inferior Colliculus: This is a midbrain structure that receives and integrates auditory information from both ears.

Primary Auditory Cortex: This is the first cortical region in the temporal lobe responsible for processing auditory information from the thalamus.

The correct sequence, therefore, is Cranial nerve VIII - Cochlear Nuclei – Medial Geniculate nucleus - Inferior Colliculus - Primary Auditory cortex.

To know more about stimulus visit:

https://brainly.com/question/298785

#SPJ11

b) Tube 1 2 3 4 5 In a submerged culture of fungi, in the presence of lipids, the OD value of --, but the OD values of different spectrophotometer was concentrations of lipase were as mentioned below: Concentration of Lipase(mg/ml) OD Values 1.25 2.50 5.00 7.50 10.00 Now, plot the value to make a standard curve and calculate the concentrations of the lipase products in the sample of the submerged culture nxhibit the release of lipase enzyme by fungi 0.320 0.435 0.498 0.531 0.626

Answers

To determine the concentrations of lipase products in a submerged culture of fungi, a standard curve can be created by plotting the concentration of lipase (mg/ml) against the corresponding OD values.

The equation of the standard curve can then be used to estimate the lipase product concentrations based on the OD value obtained from the sample. This method assumes a linear relationship between lipase concentration and OD values, and careful curve fitting may be required for accurate results if the relationship is nonlinear.

To create a standard curve and calculate the concentrations of lipase products in the sample, we will plot the concentration of lipase (in mg/ml) on the x-axis and the OD values on the y-axis.

Using the given data:

Concentration of Lipase (mg/ml): 1.25 2.50 5.00 7.50 10.00

OD Values: 0.320 0.435 0.498 0.531 0.626

Plotting these points on a graph, we can create a standard curve. The x-intercept of the curve represents the concentration of lipase in the sample.

By drawing a best-fit line or curve through the points, we can determine the equation of the line or curve. This equation will allow us to estimate the concentration of lipase products for any given OD value.

Once we have the equation of the standard curve, we can substitute the OD value obtained from the sample of the submerged culture into the equation to calculate the corresponding concentration of lipase products.

It's important to note that the standard curve and calculation of lipase product concentrations assume a linear relationship between lipase concentration and OD values. If the relationship is nonlinear, a different curve-fitting method may be needed to obtain accurate results.

To know more about lipase refer to-

https://brainly.com/question/3449211

#SPJ11

The following DNA sequences were used to generate a contig from a genome sequencing project.
ttcagattttccccg
gctaaagctccgaa
gccattaacgcc
tttagcatactacggcgtta
aaaaccggggaaaat
tccgaatcggtcattcaga
Examine the fully assembled double strand sequence. Counting bases starting at 1 for the 5'-most base of each strand, at what position is the first place where a base the same distance from each end matches? (For example if the sequence reads 5'-CACGG... from one end and 5'-GTCGA... from the other end, then the first match occurs at position 3.)

Answers

The first place where a base the same distance from each end matches in the fully assembled double strand sequence is at position 9. This is because the first base in the 5'-most strand (ttcaga) matches the ninth base in the 3'-most strand (tcagtt).

To find the first match, we can start at the 5'-most end of the sequence and count bases until we find a match with the 3'-most end of the sequence. In this case, the first match occurs at position 9.

It is important to note that this is only the first match in the sequence. There may be other matches that occur later in the sequence.

Here is a diagram of the fully assembled double strand sequence, with the first match highlighted:

5'-ttcagattttccccg-3'

| |

3'-tcagttccgaatcgg-5'

The highlighted bases are the first match in the sequence.

To know more about the double strand sequence refer here,

https://brainly.com/question/30546266#

#SPJ11

Chloroplasts, mitochondria, and bacteria have 70S ribosomes in common. O True False

Answers

70S ribosomes are a type of ribosome found in prokaryotic cells, including bacteria, as well as in certain organelles of eukaryotic cells, such as mitochondria and chloroplasts.

The term "70S" refers to the sedimentation coefficient of the ribosome, which is a measure of its size and density.

The 70S ribosome consists of two subunits: a larger 50S subunit and a smaller 30S subunit. True. Chloroplasts, mitochondria, and bacteria share the characteristic of having 70S ribosomes.

These ribosomes are smaller than the 80S ribosomes found in eukaryotic cells.

The presence of 70S ribosomes in these organelles and bacteria suggests a common evolutionary origin and supports the endosymbiotic theory.

Which proposes that mitochondria and chloroplasts were once free-living bacteria that were engulfed by ancestral eukaryotic cells. The conservation of 70S ribosomes among these organisms highlights their shared ancestry and functional similarities.

Learn more about 70S ribosome here:

https://brainly.com/question/11138488

#SPJ11

State one possible hypothesis that can explain the global distribution of lactase persistence (lactose tolerance) and lactase nonpersistance (lactose intolerance). Be sure to include the following keywords in your explanation; selection, fitness, survival.

Answers

The natural selection, fitness hypothesis suggests the global distribution of lactase persistence and non persistence may have arisen an adaptive response to availability or absence of dairy farming practices.

One possible hypothesis to explain the global distribution of lactase persistence (lactose tolerance) and lactase nonpersistence (lactose intolerance) is the "natural selection and fitness" hypothesis. This hypothesis suggests that lactase persistence may have been positively selected for in populations that traditionally relied on dairy consumption as a significant source of nutrients, while lactase non persistence may have been advantageous in populations with limited or no history of dairy farming.

In regions where dairy farming has been prevalent for thousands of years, individuals with the genetic mutation that allows for lactase persistence would have had a survival advantage. The ability to digest lactose, the sugar present in milk, would have provided a valuable source of nutrition, especially during times of scarcity or limited food resources. This increased fitness and survival among lactase-persistent individuals would have led to a higher prevalence of the lactase persistence trait in these populations over generations.

Learn more about lactase persistence here

https://brainly.com/question/32484975

#SPJ11

In human fibroblasts, the "loss" of Rb and p53 by a DNA tumor virus, and reactivation of hTERT will lead to which of the following? a. Tumorigenic phenotype b. Morphological transformation c. Immortalization d. quiescence e. crisis

Answers

The loss of Rb and p53 by a DNA tumor virus, and reactivation of hTERT will lead to immortalization. So, option C is accurate.

When human fibroblasts experience the loss of Rb and p53, which are tumor suppressor proteins, and the reactivation of hTERT (human telomerase reverse transcriptase), the cells undergo a process called immortalization. This means that the cells acquire the ability to divide indefinitely, bypassing the usual cellular senescence mechanisms. Rb and p53 are key regulators of the cell cycle and are responsible for suppressing abnormal cell growth and promoting cell cycle arrest or apoptosis in response to DNA damage or other stressors. The loss of their function eliminates these control mechanisms, while the reactivation of hTERT prevents the progressive shortening of telomeres, which are protective caps at the ends of chromosomes that shorten with each cell division. Consequently, the combination of Rb and p53 loss and hTERT reactivation leads to cellular immortalization, a critical step in the development of a tumorigenic phenotype.

To know more about DNA tumor virus

brainly.com/question/13063863

#SPJ11

What are the five principal reactions that occurred during
primodial nucleosynthesis?
Name all the types of stable nuclei that remained after
primordial nucleosynthesis had finished.
At what proportio

Answers

At the end of primordial nucleosynthesis, the universe was composed of approximately 75% hydrogen, 24% helium, and trace amounts of lithium and other elements.

During primordial nucleosynthesis, the five principal reactions that occurred are as follows:Proton-proton chain reaction: This reaction occurs when protons fuse with one another to form a helium nucleus.Alpha process: It is a sequence of nuclear reactions that produce helium-4 from hydrogen. This process involves the capture of helium nuclei to heavier elements. The alpha process is most efficient at producing elements with even numbers of protons, particularly helium, carbon, and oxygen.Beta decay: It is a process by which an unstable atomic nucleus loses energy by emitting an electron or a positron.

The unstable nucleus changes into a stable nucleus by emitting either a negatively charged electron (beta-minus decay) or a positively charged positron (beta-plus decay).Neutron capture: It is a process in which a neutron is added to a nucleus to produce a heavier nucleus. Neutron capture is important for the formation of heavier elements beyond iron.Nuclear fusion: It is a process by which multiple atomic nuclei join together to form a heavier nucleus. This is the process by which stars produce energy.The types of stable nuclei that remained after primordial nucleosynthesis had finished are as follows:Hydrogen-1, Helium-3, Helium-4, Lithium-6, Lithium-7, Beryllium-7.At the end of primordial nucleosynthesis, the universe was composed of approximately 75% hydrogen, 24% helium, and trace amounts of lithium and other elements.

learn more about hydrogen

https://brainly.com/question/24613652

#SPJ11

Fibrous proteins Fibrous and globular proteins Globular proteins Answer Bank primarily function as structural proteins includes collagen includes hemoglobin exhibit secondary protein structure somewhat spherical in shape rod-like in shape insoluble in water some function as enzymes polymers of amino acids soluble in water

Answers

Fibrous proteins are rod-shaped and insoluble in water. These types of proteins primarily function as structural proteins in living organisms, such as keratin, collagen, and elastin.

Globular proteins, on the other hand, are soluble in water and have a somewhat spherical shape. Hemoglobin and enzymes are examples of globular proteins that exhibit a secondary protein structure.
Fibrous proteins and globular proteins are two of the major protein categories. Structural proteins, such as collagen, keratin, and elastin, are primarily made up of fibrous proteins. The insoluble characteristic of fibrous proteins gives them a significant structural advantage because they can withstand and resist external forces. The tight packing of the amino acid residues, as well as their repeated sequences, results in the fibrous protein's overall shape and strength. On the other hand, globular proteins, such as hemoglobin and enzymes, are folded into a compact, spherical shape, making them soluble in water. This shape allows globular proteins to interact with water molecules while still maintaining their 3D structure. As a result, globular proteins are involved in various biochemical reactions in living organisms. As enzymes, they can catalyze metabolic reactions, whereas, as transporters, they can shuttle molecules around the body.

Fibrous proteins are usually involved in providing structural support to cells, tissues, and organs. The strength and resistance of these proteins come from their repeating sequences and the tight packing of amino acid residues. Globular proteins, on the other hand, are involved in a variety of biochemical functions, including enzymatic reactions and transportation of molecules. The protein's compact, spherical shape allows for interactions with water molecules while maintaining its 3D structure.

To know more about Fibrous proteins visit:

brainly.com/question/31601239

#SPJ11

What is the body mass index? a. an index of body fat relative to height b. a measure of aerobic fitness relative to body weight c. an index of body weight relative to height d. a measure of blood glucose relative to body weight

Answers

The body mass index (BMI) is an index of body weight relative to height. It is a numerical value calculated by dividing an individual's weight in kilograms by the square of their height in meters (BMI = weight (kg) / height^2 (m^2)). The correct answer is option c.

The body mass index serves as a tool to assess whether an individual's weight falls within a healthy range based on their height.

It is widely used as a screening tool to evaluate weight status and potential health risks associated with underweight, normal weight, overweight, and obesity.

BMI is useful because it provides a quick and simple measure to categorize individuals into different weight categories. These categories are commonly defined as follows:

Underweight: BMI less than 18.5

Normal weight: BMI between 18.5 and 24.9

Overweight: BMI between 25.0 and 29.9

Obesity: BMI 30.0 and above

It's important to note that the BMI is an indicator of body weight relative to height and does not directly measure body fat percentage or other factors related to health.

While BMI can be a useful initial screening tool, it may not provide a complete assessment of an individual's health status. Other factors such as body composition, muscle mass, and distribution of fat can influence overall health.

For instance, individuals with higher muscle mass may have a higher BMI even if they have a lower percentage of body fat. Additionally, BMI does not take into account differences in body shape or fat distribution, which can affect health risks.

For a more comprehensive evaluation of an individual's health, additional measurements and assessments, such as body fat percentage, waist circumference, and overall health indicators, may be necessary.

In summary, the body mass index (BMI) is an index of body weight relative to height. It is used as a quick and simple screening tool to assess weight status and potential health risks associated with underweight, normal weight, overweight, and obesity.

While BMI provides a useful initial measure, it is important to consider other factors, such as body composition and overall health indicators, for a comprehensive assessment of an individual's health.

Learn more about body mass index at: https://brainly.com/question/2064513

#SPJ11

From your General Cell Biology, which substrate binds to the Rab-Ran-Ras-Rac-Cdc42-Rho family of proteins that is crucial for the activation of that enzyme? a. GTP.
b. ATP. c. GDP.
d. ADP.

Answers

The substrate that binds to the Rab-Ran-Ras-Rac-Cdc42-Rho family of proteins and is crucial for their activation is GTP.

Option (a) is correct.

The Rab-Ran-Ras-Rac-Cdc42-Rho family of proteins are small GTPases that play important roles in cellular signaling and regulation. These proteins undergo a cycle of activation and inactivation by binding to either GTP (guanosine triphosphate) or GDP (guanosine diphosphate).

The active form of these proteins, which allows them to carry out their functions in signaling pathways, is when they are bound to GTP. When GTP is bound, the GTPase is in the "on" or active state. On the other hand, when GDP is bound, the GTPase is in the "off" or inactive state.

The exchange of GDP for GTP and the subsequent hydrolysis of GTP to GDP is regulated by specific guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), respectively.

To activate the Rab-Ran-Ras-Rac-Cdc42-Rho family of proteins, GTP must bind to these proteins, leading to a conformational change that allows them to interact with downstream effectors and initiate signaling cascades.

Therefore, the correct option is (a) GTP.

To learn more about GTP  here

https://brainly.com/question/32237072

#SPJ4

Vertebrate Phylogeny: overarching themes Be able to identify novel morphological innovations that distinguish the major vertebrate groups. Be able to construct an accurate, simple branch diagram that includes the major vertebrate groups and key diagnostic characters at each node and within each group. Example of a node- gnathostomes; characters-jaws, paired appendages, tetrameric hemoglobin, etc. Within group characters-e.g., Chondrichthyes; characters-placoid scales, cartilaginous endoskeleton. Sauropsid vs synapsid: distinguishing morphological differences (take an organ system approach-example: Compare and contrast the functional and structural patterns of skull morphology, jaw musculature, dentition, secondary palate, and muscle attachment sites between a typical sauropsid/diapsid and advanced synapsid amniote) How can embryology help decipher patterns of vertebrate phylogeny: use specific examples from various organ systems to support your answer. Think of recaptitulation in ontogeny of the vertebrate venous system or aortic arches.

Answers

Sauropsids and synapsids are two major clades of tetrapods. They are distinguished by a number of morphological features.

How to explain the information

Sauropsid skulls have a single temporal opening, while synapsid skulls have two temporal openings.

Sauropsid skulls are more kinetic than synapsid skulls, meaning that they can move more freely.

Embryology can help decipher patterns of vertebrate phylogeny by studying the developmental patterns of different vertebrate groups.

The study of vertebrate phylogeny is a complex and fascinating field. By studying the morphological, developmental, and molecular evidence, scientists have been able to reconstruct the evolutionary history of vertebrates.

Learn more about tetrapod on

https://brainly.com/question/15744567

#SPJ4

1) Which type of study compares people with and without a disease?
a) Cohort b) Descriptive observational c) Case-control d) Ecologic
2) In which type of study is the group the level of analysis?
a) Cohort b) Descriptive observational c) Case-control d) Ecologic
3) Which of the following measures existing cases in a population?
a) Prevalence b) Delta c) Incidence d) Duration
4) What is the term for a disease or condition that is associated with a particular region?
a) Endemic b) Outbreak c) Cluster d) Epidemic

Answers

1) The study compares people with and without a disease, answer to this question is option c) Case-control. 2. The answer to this question is option a) Cohort. Cohort studies are observational in nature, meaning they are not conducted under controlled conditions. 3. The answer to this question is a) Prevalence. 4. The answer to this question is a) Endemic.

1) A case-control study is an observational study in which two existing groups varying in outcome are identified and compared based on some supposed causal attribute. Case-control studies are generally designed to determine if there is an association between the exposure to a particular risk factor and the outcome of interest. The investigator identifies the cases in the population who have the disease or outcome of interest and selects a group of suitable control individuals from the same population without the outcome of interest.

2)The answer to this question is a) Cohort. Cohort studies are observational in nature, meaning they are not conducted under controlled conditions. Cohort studies track one or more groups of individuals over time to assess an exposure or treatment's relationship with an outcome. They are often used to track disease incidence or the development of new outcomes. In cohort studies, the group is the level of analysis, and it is compared to another group.

3) The answer to this question is a) Prevalence. Prevalence measures existing cases in a population, reflecting the total number of individuals who have the condition, regardless of when they acquired it. It is a proportion of the number of individuals in the population with the disease at a particular time compared to the total number of people in the population.

4) The answer to this question is a) Endemic. Endemic diseases are those that are associated with a particular region or population. They are the illnesses that are present in a specific geographical location or population group. An endemic disease is one that is constantly present in a given population. An outbreak, on the other hand, is an epidemic limited to a small geographic area. A cluster is a grouping of disease cases that occur more frequently than expected in a given location and time.

To know more about disease click here:

https://brainly.com/question/943439

#SPJ11

Pericardial effusion: Please define and describe this diagnosis.
Please name 4 possible causes for this diagnosis. 1-2
paragraph.

Answers

Pericardial effusion is the accumulation of fluid around the heart, which can impair its functioning. It can be caused by factors such as inflammation, heart attack, cancer, and kidney failure.

Pericardial effusion refers to the accumulation of fluid in the pericardial sac, the double-layered membrane that surrounds the heart. It can exert pressure on the heart, impairing its ability to pump blood effectively.

Pericardial effusion can be caused by various factors. Four possible causes include:

Inflammation: Inflammation of the pericardium, known as pericarditis, can lead to pericardial effusion. It may occur due to viral or bacterial infections, autoimmune disorders, or certain medications.

Heart attack: Myocardial infarction (heart attack) can cause damage to the heart muscle, leading to pericardial effusion.

Cancer: Certain types of cancer, such as lung cancer or breast cancer, can metastasize to the pericardium and result in fluid accumulation.

Kidney failure: In some cases, kidney failure can cause an imbalance in fluid levels, leading to pericardial effusion.

To know more about Pericardial effusion, refer to the link:

https://brainly.com/question/32253561#

#SPJ11

The following shows DNA profiles from a father and his 4 children. Which is the father, and which are the children? Write "F" under the father’s DNA.
--- --- ---
---
--- ---
----
---- ---- ----
F
What is the minimum # of mothers of the children? Explain

Answers

The father's DNA profile is indicated by the "F" in the given sequence. The minimum number of mothers for the children is one.

Based on the given DNA profiles, we can determine the father and children by comparing the DNA sequences. The father's DNA profile is indicated by the "F" in the sequence. The remaining DNA profiles represent the children.

To determine the minimum number of mothers, we need to analyze the similarities and differences among the children's DNA profiles. If all the children share the same DNA profile, it indicates that they have the same mother. In this case, since the DNA profiles of the children are not provided, we cannot make a definitive conclusion about the number of mothers based on the information given.

However, it is important to note that even if the children have different DNA profiles, it does not necessarily imply multiple mothers. Genetic variation can occur due to recombination and mutation during DNA replication, resulting in differences among siblings' DNA profiles while still having the same biological mother.

Therefore, based on the information given, we cannot determine the minimum number of mothers for the children.

Learn more about DNA profile here: https://brainly.com/question/7456047

#SPJ11

Achondroplasia is caused by mutations in the Fibroblast growth factor receptor 3 gene. It is a disorder of bone growth that prevents the changing of cartilage to bone. O Statement 1 is correct. Statement 2 is incorrect Both statements are incorrect Statement 1 is incorrect. Statement 1 is correct. Both statements are correct Neurofibromatosis 1 is considered an autosomal dominant disorder because the gene is located on the long arm of chromosome 17. It is caused by microdeletion at the long arm of chromosome 17 band 11 sub-band 2 involving the NF1 gene. Both statements are incorrect O Both statements are correct O Statement 1 is correct. Statement 2 is incorrect O Statement 1 is incorrect, statement 2 is correct Genetic disorder is a disease that is caused by an abnormality in an individual's DNA. Range from a small mutation in DNA or addition or subtraction of an entire chromosome or set of chromosomes. O Both statements are correct Statement 1 is correct. Statement 2 is incorrect O Statement 1 is incorrect, statement 2 is correct O Both statements are incorrect.

Answers

The correct option is "Statement 1 is correct, Statement 2 is incorrect."Genetic disorders are diseases caused by abnormalities in an individual's DNA.

They can range from a small mutation in DNA to the addition or subtraction of an entire chromosome or set of chromosomes.Achondroplasia is a disorder of bone growth that prevents the changing of cartilage to bone. It is caused by mutations in the Fibroblast growth factor receptor 3 gene.

Statement 1 is correct about Achondroplasia.Neurofibromatosis 1 is caused by microdeletion at the long arm of chromosome 17 band 11 sub-band 2 involving the NF1 gene. Neurofibromatosis 1 is considered an autosomal dominant disorder because the gene is located on the long arm of chromosome 17. Statement 2 is incorrect about Neurofibromatosis 1.

To know more about diseases visit:

https://brainly.com/question/17950058

#SPJ11

1 point If glucagon production stopped which of the following would be observed? Enhanced production of bile Increased absorption of glucose from the small intestine Increased release of lipids from the liver Decreased release of glucose from the liver and muscle cells Increased production of insulin * 1 point Chronic untreated type 2 diabetes can lead to which of the following conditions? High blood glucose High blood pressure leading to glomerular damage Obesity The excretion of hyper-concentrated urine Hypoglycemia

Answers

If glucagon production stopped, the following would be observed: Decreased release of glucose from the liver and muscle cells. Glucagon is a hormone produced by alpha cells of the pancreas and is involved in regulating glucose homeostasis.

Glucagon regulates glucose production in the liver, and its effects are opposite to insulin. When glucagon is produced, it inhibits insulin production and causes an increase in glucose production in the liver.

Hence, if glucagon production stopped, there would be a decrease in glucose production from the liver and muscle cells. This would result in the inability of the body to maintain blood glucose levels.

Chronic untreated type 2 diabetes can lead to high blood glucose. This condition is characterized by the inability of the body to regulate glucose levels. In type 2 diabetes, insulin production is affected, which leads to an inability to manage glucose levels.

The result of this is high blood glucose levels that can lead to further complications if left untreated. Some of the complications of untreated type 2 diabetes include kidney damage, nerve damage, cardiovascular disease, and vision problems.

Therefore, it is important to manage diabetes effectively to avoid these complications.

To know more about glucagon visit;

brainly.com/question/17438442

#SPJ11

Explain when a behavior (for example, a fear) becomes a diagnosable disorder What is a phobia? Can you name five specific ones with their medical terms? 2. What is the difference between aphagia and aphasia? 3. Define-acoustic, otic, achromatic vision, presbyopia. 4. Have you heard of LASIK surgery? Do you know what is involved?

Answers

When does a behavior become a diagnosable disorder? A behavior becomes a diagnosable disorder when it meets the following criteria:

The behavior or response is persistent and excessive, (2) the behavior results in significant distress or impairment, and (3) the behavior is not a result of a medication, substance abuse, or a medical condition. What is a phobia? A phobia is a type of anxiety disorder characterized by an excessive or irrational fear of a particular object or situation that causes significant distress and impairment in daily functioning. Five specific phobias with their medical terms are:(1) Arachnophobia (fear of spiders)(2) Acrophobia (fear of heights)(3) Claustrophobia (fear of confined spaces)(4) Agoraphobia (fear of open spaces or crowds)(5) Aerophobia (fear of flying)What is the difference between aphagia and aphasia? Aphagia is a medical term used to describe a disorder in which a person is unable to swallow food or liquids, while aphasia is a disorder in which a person is unable to communicate or understand language due to brain damage.

To know more about behavior visit:

https://brainly.com/question/29569211

#SPJ11

To reproduce sexually, an organism must create haploid [1] cells, or [2], from diploid cells via a specialized cell division called [3]. During mating, the father's haploid cells, called [4] in animals, fuse with the mother's haploid cells, called [5]. Cell fusion produces a diploid cell called a [6], which undergoes many rounds of cell division to create the entire body of the new individual. The cells produced from the initial fusion event include [7] cells that form most of the tissues of the body as well as the [8]-line cells that give rise to the next generation of progeny. Allele, bivalent, germ, pedigree, pollen, meiosis, gametes, somatic, eggs, zygote, mitosis, sperm 1. 2. 3. 4. 5. 6. 7. 8.

Answers

1. gametes: Gametes are haploid cells that are involved in sexual reproduction. They contain half the number of chromosomes compared to diploid cells.

2. sperm: Sperm is the male gamete in animals. It is a specialized haploid cell produced by the male reproductive system.

3. meiosis: Meiosis is a specialized cell division process that occurs in reproductive cells to produce gametes. It involves two rounds of division, resulting in the formation of four haploid cells.

4. sperm: In animals, the father's haploid cells are called sperm. Sperm is produced in the testes and carries genetic information from the father.

5. eggs: In animals, the mother's haploid cells are called eggs. Eggs are produced in the ovaries and carry genetic information from the mother.

6. zygote: When the sperm and egg fuse during fertilization, they form a diploid cell called a zygote. The zygote contains a complete set of chromosomes (one set from each parent) and develops into a new individual.

7. somatic: Somatic cells are the non-reproductive cells in an organism that make up most of its body tissues. These cells are diploid and do not participate in the formation of gametes.

8. germ: Germ cells are the specialized cells that give rise to gametes. These cells undergo cell divisions to produce the next generation of progeny and are responsible for transmitting genetic information to offspring.

To know more about gametes visit:

https://brainly.com/question/29600905

#SPJ11

Why taxonomic nomenclature is important? It provides the unified language for communication about biological diversity. It reflects evolutionary relatedness of taxa. Scientific names often capture important characteristics of the animals. It documents the history of science. All of the above.

Answers

Taxonomic nomenclature is important because it provides a standardized language for communication, represents evolutionary relationships, captures important characteristics, and documents the history of scientific discoveries. So, All of the above is the correct choice.

Taxonomic nomenclature is important for several reasons:

It provides a unified language for communication about biological diversity: By assigning unique scientific names to organisms, taxonomic nomenclature allows researchers, scientists, and other professionals to communicate and exchange information accurately and precisely. This ensures clarity and avoids confusion that may arise from using different common names for the same species.It reflects evolutionary relatedness of taxa: Taxonomic nomenclature is based on the principles of evolutionary relationships. Organisms with similar characteristics and shared ancestry are grouped together into taxa (such as genus, family, order, etc.), and their scientific names reflect their evolutionary relationships. This helps in understanding the evolutionary history and biological relationships between different organisms.Scientific names often capture important characteristics of the animals: Scientific names are often chosen to describe important characteristics of the organisms they represent. These names can provide insights into the morphology, behavior, habitat, or other significant features of the species. This additional information enhances our understanding of the organism beyond its common name.It documents the history of science: Taxonomic nomenclature has a long history and has evolved over time. The use of scientific names allows us to trace the development of scientific knowledge, discoveries, and advancements in the field of taxonomy. The history of taxonomic naming provides valuable insights into the progression of scientific understanding and serves as a record of scientific exploration.

To know more about Taxonomic nomenclature

brainly.com/question/12074909

#SPJ11

Which statement below best describes a characteristic of an Alu
element?
a.Alu is typically transcribed by RNA pol III.
b.Alu is reverse transribed by L1 ORF1p.
c. Alu is an autonomous retrotransposon

Answers

Among the given statement, the best statement that describes a characteristic of an Alu element is "Alu is typically transcribed by RNA pol III."

Alu is the short interspersed nuclear element, which is 300 bp in length and is the most common repetitive element found in the human genome. Alu is classified under the group of retrotransposons, which are genetic elements that can move from one location to another location in the genome. Retrotransposons are the significant contributor to the genomic diversity of mammals.

Transcription of Alu elements, Alu elements are transcribed by RNA polymerase III (Pol III). RNA Pol III is a large complex enzyme that is responsible for the transcription of tRNAs, 5S rRNA, and other small untranslated RNA molecules.Alu elements are transcribed as RNA molecules, and these RNA molecules are the primary source of various small RNA molecules found in cells. After transcription, Alu RNA molecules fold back on themselves and form a hairpin structure that is stabilized by base pairing. These hairpin structures are recognized by the RNA-processing machinery, which cleaves them into small RNA molecules called Alu RNAs. Therefore, the correct statement among the given statement is "Alu is typically transcribed by RNA pol III."

to know more about Retrotransposons here:

brainly.com/question/30672463

#SPJ11

15) UTI's with microbial etiology include: A. cystitus. B. Urethritis C. Leptospirosis D. A and B E. A, B and C 16) The cause of gonorrhea is a member of the genus: A. Borrelia B. treponema C. Neisseria D. Mycobacterium E. plasmodium 17) Which antibody is most import in immediate hypersensitivity reactions: A. IgG B. IgM C. IgA D. ISE 18) Which is true. Of. HPV (papillomavirus) A. Only two strains. Effect humans B. It can cause genital warts C. Less than 1% of women are effected D. No vaccine is available 19). Trichomonal. Vaginitis is caused by: A. Yeast B. Bacteria C. Protozoan D. Chlamydia E. A virus 20) Lyme disease A. Is highly contagious B. Early symptoms include rash and flu like symptoms etiology D. Mosquito vector C. Viral

Answers

UTIs with microbial etiology include cystitis and urethritis. The cause of gonorrhea is a member of the genus Neisseria. The most important antibody in immediate hypersensitivity reactions is IgE.

UTIs (urinary tract infections) with microbial etiology commonly involve cystitis (inflammation of the bladder) and urethritis (inflammation of the urethra). These infections are often caused by bacterial pathogens.

Gonorrhea is caused by a member of the genus Neisseria, specifically Neisseria gonorrhoeae, a sexually transmitted bacterium.

In immediate hypersensitivity reactions, the most important antibody involved is IgE. IgE antibodies are responsible for triggering allergic reactions and are associated with conditions like asthma and allergic rhinitis.

HPV (human papillomavirus) is a sexually transmitted infection that can cause genital warts and is also associated with certain types of cancer. There are several strains of HPV that affect humans, not just two, and there is a vaccine available to protect against certain high-risk strains.

Trichomonal vaginitis, also known as trichomoniasis, is caused by a protozoan parasite called Trichomonas vaginalis.

Lyme disease is primarily transmitted through the bite of infected black-legged ticks. It is not highly contagious between humans. Early symptoms of Lyme disease often include a characteristic rash called erythema migrans, along with flu-like symptoms.

Learn more about Gonorrhea here:

https://brainly.com/question/32219831

#SPJ11

27. What does Lugol's test for and a + color? + 28. What does Biuret test for and a + color? + 29. What does benedicts test for and a + color? +

Answers

Lugol's test is used to test for the presence of starch. A positive result is indicated by a dark blue or purple color.Biuret test is used to test for the presence of proteins. A positive result is indicated by a violet or purple color.Benedict's test is used to test for the presence of reducing sugars.

Lugol's test is used to detect the presence of starch in a solution. The test is performed by adding a few drops of Lugol's iodine solution to the solution in question. If the solution turns dark blue or purple, the presence of starch is confirmed.

Biuret test, on the other hand, is used to test for the presence of proteins in a solution. When Biuret reagent is added to a protein solution, the solution turns violet or purple in color. The intensity of the color is proportional to the amount of protein present in the solution.

Benedict's test is used to detect the presence of reducing sugars in a solution. When Benedict's solution is added to a reducing sugar solution and heated, a red, yellow, or green color is formed, depending on the amount of reducing sugar present. The more intense the color, the more reducing sugar is present.

In summary:Lugol's test is used to test for the presence of starch. A positive result is indicated by a dark blue or purple color.Biuret test is used to test for the presence of proteins. A positive result is indicated by a violet or purple color.Benedict's test is used to test for the presence of reducing sugars. A positive result is indicated by a red, yellow, or green color.

To know more about Lugol's test visit-

brainly.com/question/31848174

#SPJ11

This is a essay-formed question. Please feel free to elaborate
(worth 17 marks)
From the course BMOL3402 Molecular Biology and Genomics and BMOL
6432 Molecular Biology and Genomics
Bacteria frequently

Answers

We can see here that in order to write an essay on the topic, here is a guide:

Carry a research on the given topic.Make an outline to help your essay.Clearly define important terms.
What is essay?

An essay is a piece of writing that presents a focused argument or analysis on a specific topic. It is a common form of academic writing that allows individuals to express their thoughts, ideas, and opinions on a particular subject matter.

Essays typically have a clear structure and follow a logical progression. They usually consist of an introduction, body paragraphs, and a conclusion. The introduction introduces the topic and provides context, while the body paragraphs present arguments, evidence, and analysis to support the main thesis or claim.

Learn more essay on https://brainly.com/question/11606608

#SPJ4

How is the costimulatory molecule different for T1-2 antigens (what provides the costimulatory signal)?
A CD40L
B mitogen
c. extensive receptor cross-linking
D 87
What does perforin do?
A
Activate B cells
B) Protein that forms pores in membrane
c. Causes inflammation
d. Transports antigen to the lymph nodes

Answers

B). Costimulatory molecules play an important role in the activation of T cells. When an antigen binds to a T cell receptor, it sends an activation signal to the T cell. However, this signal is not enough to fully activate the T cell. The costimulatory molecule provides a second signal to fully activate the T cell.

There are different costimulatory molecules for T1-2 antigens. The costimulatory molecule that provides the costimulatory signal for T1-2 antigens is extensive receptor cross-linking. This is a type of signal that occurs when a large number of antigens bind to the T cell receptors at the same time. This signal helps to ensure that the T cell is activated only when there is a high level of antigen present.

Perforin is a protein that forms pores in membranes. It is released by cytotoxic T cells and natural killer cells as part of the immune response. Perforin helps to destroy cells that have been infected by viruses or other intracellular pathogens. It does this by creating pores in the cell membrane, which causes the cell to lose its structural integrity and die.  

To know more about Costimulatory molecules  visit:-

https://brainly.com/question/33359771

#SPJ11

Three Identical Strangers (2018) Two of the brothers were reported to show behaviors indicating emotional distress shortly after they were adopted at 6 months. What upsetting behavior did they display?

Answers

In the documentary "Three Identical Strangers" (2018), two of the adopted brothers displayed behaviors indicating emotional distress shortly after their adoption at 6 months.

The specific upsetting behavior they exhibited was "separation anxiety." Separation anxiety refers to a condition where individuals, often children, experience excessive fear or distress when separated from their primary caregivers or attachment figures. It is characterized by clinginess, distress, crying, and a strong desire to be in close proximity to their caregivers. The brothers' display of separation anxiety indicated their emotional turmoil and the challenges they faced in adjusting to their new environment after being separated from their biological family.

Learn more about Identical Strangers here:

https://brainly.com/question/33279524

#SPJ11

Other Questions
please solve and show workingsb) Consider a linear transformation \( T(x, y)=(x+y, x+2 y) \). Show whether \( T \) is invertible or not and if it is, find its inverse. Q5Question 5 What is the Australian standard number for tensile testing (i.e.) "metallic materials - tensile testing at ambient temperatures"? An industrial plant absorbs 500 kW at a line voltage of 480 V with a lagging power factor of 0.8 from a three-phase utility line. The apparent power absorbed is most nearly O a. 625 KVA O b. 500 KVA O c. 400 KVA O d. 480 KVA A fluid in a fire hose with a 46.5 mm radius, has a velocity of 0.56 m/s. Solve for the power, hp, available in the jet at the nozzle attached at the end of the hose if its diameter is 15.73 mm. Express your answer in 4 decimal places. The "_________" Act of 1976 instructed the Secretary of the Interior to assess roadless areas of 5,000 acres or more, and make recommendations as to the suitability of those lands for wilderness designation. A 2mx 2m solar absorber plate is at 400 K while it is exposed to solar irradiation. The surface is diffuse and its spectral absorptivity is a = 0, for >1 >0.5 m a=0.8, for 0.5 u m> > m a = 0, for lym> > 2um a =0.9 for 1 > 2 m Determine absorptivity, reflectivity and emissivity of the absorber plate (15 points) If a cell has a diploid number of twelve (2N = 12) beforemeiosis, how many chromosomes will be in each of the four daughtercells if one pair of chromosomes experiences nondisjunction duringmeiosis 3. (10 points) At 448 C the equilibrium constant Kc for thereaction is 50.5. Predict in which direction the reaction proceedsto reach equilibrium if we start with 0.10M HI, 0.020M H2 and 0.30MI2. _____________ lacks a defined primary structure and is not considered a polysaccharide. a.Hemicellulose b.Cellulose c.Lignin d.Pectin Sketch a 1D, 2D, and 3D element type of your choice. (sketch 3 elements) Describe the degrees of freedom per node and important input data for each structural element. (Material properties needed, etc Describe the key characteristics of oncogene and tumour suppressor gene mutation, and how these characteristics impact on the strategies used to target cells with these mutations. 1. (a) Let A and B be two events. Suppose that the probability that neither event occurs is 3/8. What is the probability that at least one of the events occurs? (b) Let C and D be two events. Suppose P(C)=0.5,P(CD)=0.2 and P((CD) c)=0.4 What is P(D) ? Paper ClipFor each component of the materials used in the paper clip, explore the following:Emphasis on material selection, process selection, and cost of manufacturing.Examine the advantages, disadvantages, and costs of the materials used?Study the bending method for manufacturing the paper clip.Determine at what stage of manufacture and by which method should the surface treatment be performed.Determine the final coating of the paper clip. Designing vaccines to elicit drugs?Could we somehow create a vaccine to have the immune system target and attack cocaine molecules once they are present in us?Designing vaccines to melanoma cancer?Could we somehow create a vaccine to have the immune system target and attack molecules only found on cancer cells like melanoma?What challenges might you face with attempting to elicit an effective immune response to the melanoma cancer?What other signals are missing to ACTIVATE this T helper cell? Why or why not?What benefits do you see in this system of shutting off cells that are stick to things that are NOT associated with PAMP detection?B cells:What is the function of a B cell once active?What is required for B cell activation?Explain the process based on your understanding?What is the difference between a B cells antigen receptor and its antibodies?B cells require T helper cell help (binding) for full activation. But which helper cell?How does your immune system use antibodies?In other words, what are the functions of antibodies?What is the difference between passive and active immunity? A vapor-compression refrigeration system utilizes a water-cooled intercooler with ammonia as the refrigerant. The evaporator and condenser temperatures are -10 and 40C, respectively. The mass flow rate of the intercooler water is 0.35 kg/s with a change in enthalpy of 42 kJ/kg. The low-pressure compressor discharges the refrigerant at 700 kPa. Assume compression to be isentropic. Sketch the schematic and Ph diagrams of the system and determine: (a) the mass flow rate of the ammonia refrigerant, (b) the capacity in TOR, (c) the total compressor work, and (d) the COP. ASAP plsIf the rotation of the wheel is defined by the relation: 0 = 3t3 - 5t + 7t - 2, where 0 is in radians and t in seconds. When t = 3 seconds, find the value of angular acceleration in radians/s 42 4 To design a simply supported RCC slab for a roof of a hall 4000x9000 mm inside dimension, with 250 mm wall all around, consider the following data: d= 150 mm, design load intensity=15 kN/m, M25, Fe415. a. Find the effective span and load per unit width of the slab. b. Find the ultimate moment per unit width of the slab. c. Find the maximum shear force per unit width of the slab. d. Find the effective depth required from ultimate moment capacity consideration and comment on the safety. e. Is it necessary to provide stirrups for such a section? Arthropods have tagma and jointed appendages. Sketch and explain how a typical Hexapod differs from a Crustacean. List at least 5 differences and 2 shared traits along with the overall comparison to body plan organization and unique features. Numerical Integration The function f(x)=e* can be used to generate the following table of unequally spaced data = x O 0.1 0.3 0.5 0.7 0.95 1.2 f(x) 1 0.9048 0.7408 0.6065 0.4966 0.3867 0.3012 . = describe massively parallel computing and grid computing and discuss how they transform the economics of supercomputing.