Explain why chemogenetic based methods of regulating cellular signaling result in poor temporal control of biochemical pathways relative to optogenetic based methods.

Answers

Answer 1

Answer:

They use different detecting methods to assess neuronal circuits

Explanation:

Chemogenetics is a technique widely used in neuroscience research to explore signaling interactions by means of genetically modified receptors capable of interacting with small molecules. Chemogenetics was first used to determine the function of the chalcone isomerase gene by inducing mutations that altered its substrate specificity. On the other hand, optogenetics is a bioluminescence-driven genetic technique used to control genetically modified neurons that express light-gated ion channel genes. This technique is also used to monitor neuronal networks. In consequence, optogenetic and chemogenetic techniques have recently been combined in order to analyze neuronal circuits, it by analyzing the same actuator molecule.


Related Questions

Which of the following is a human-related release of greenhouse gases?
O A. Wild animal respiration
OB. Volcanic eruptions
O C. Intensive agriculture
O D. Solar cycles
It’s A

Answers

Answer:

C

Explanation:

I'm pretty sure it's actually C and not A. It's asking for human-related release from greenhouse gases. Humans don't cause volcanic eruptions and aren't in control of wildlife's respirations. The solar cycles has to do with the magnetic flux that rises to the surface of the sun and lasts 11 years. Intensive agriculture increases pollution which harms the environment.

In pea plants, purple flower color, C, is dominant to white flower color, c. The table shows the frequencies of the dominant and recessive alleles in three generations of peas in a garden. Allele Frequency for Flower Color in Peas Generation p q 1 0.60 0.40 2 0.64 0.36 3 0.75 0.25 4 0.80 0.20 Which generation showed the greatest frequency of having one of each allele? generation 1 generation 2 generation 3 generation 4

Answers

Answer:

generation 1

Explanation:

The allele frequency is a term that represents the frequency that an allele can appear in a given population. This term can help to develop conclusions about the genetic diversity that a region presents in relation to the individuals that compose it.

In relation to the question above, generation 1 had the highest frequency of having one of each allele. This is because this generation presents the maximum frequency of the dominant and recessive alleles in a coherent way, 0.60 and 0.40. However, the other generations showed a steady and progressive decrease in the recessive allele.

Answer:

Gen 1 or A

Explanation:

Please give me brainliest I need l  need to level up.

Is Natural law theory is inconsistent with a theory of human rights. True / False

Answers

Answer:

i think that it's false.

Explanation:

Natural law is a theory in ethics and philosophy that says that human beings possess intrinsic values that govern our reasoning and behaviour. Natural law maintains that these rules of right and wrong are inherent in people and are not created by society or court judges.

The Interests Theory Approach. Advocates of the interests theory approach argue that the principal function of human rights is to protect and promote certain essential human interests. Securing human beings' essential interests is the principal ground upon which human rights may be morally justified.

During which period did humans first appear on Earth? Quaternary Neogene Paleogene Cenozoic

Answers

Answer:

the answer is actually Quaternary, please double check your answer before giving them out to people

we dont want them to get a bad grade

Explanation:

i took the test

E2020

A new species is descovered and scientists are trying to calssify it. One of the key features found is that the species is entirely dependent on other organisms for its fodd necessary to ssutain life. What type of species is this? A. Autotrophic B. Heterotrophic C. Producer D. Mixotrophic

Answers

Answer:

B. Heterotrophic

Explanation:

Heterotrphic animals depend on other orgamisms for food. They are made of carnaviors and omnavores. They eat other animals for food.

16. Figure it shows the digestive system
С
D​

Answers

Answer:

Is there any picture or diagram to go with this question?

Knowing the epidemiology and causative agent of Legionaries disease what questions would you ask of the victims or of their surviving relatives?

Answers

Answer:

Answered below

Explanation:

Legionnaires disease is a type of lung inflammatory disease or pneumonia, which is caused by infection from the bacteria Legionella bacterium.

Legionella bacterium can be spread by inhalation from water or soil. People with weakened immune systems are most susceptible as are smokers. Untreated legionnaires disease can progress to a fatality.

Some of the questions to ask of a victim or of surviving relatives include;

1) Any visits to swimming pools?

2) Source of drinking water?

3)Any visits to fountains?

4) Contacts with victims and their personal belongings?

5)Is any relative or victim immunocompromised? Do they have diseases that might lower their immune response?

6) Are they smokers?

Select the correct answer.
Which statement best compares the role of meiosis in a unicellular and a multicellular organisms?
OA.
Meiosis is the mechanism used for producing somatic cells in unicellular as well as multicellular
OB.
Meiosis is the mechanism used for producing gametes in unicellular organisms and somatic cells
O c.
Meiosis is the mechanism used for producing gametes in multicellular organisms whereas it doe
unicellular organisms.
Reset
Next​

Answers

Answer:

Meiosis is the mechanism used for producing gametes in multicellular organisms whereas it does

unicellular organisms.

Explanation:

Meiosis is a kind of cell division used mainly by sexually-reproducing organisms, whether unicellular or multicellular, to produce gametes i.e. meiosis only occurs during gamete formation.

In sexual reproduction, gametes must fuse in a process called fertilization. This gametes, however, must each possess half of the chromosome number of the individual organism. Meiosis is the process that ensures that the chromosome number of the gametes is reduced by half i.e. diploid (2n) to haploid (n).

Therefore, meiosis is the process of gamete formation in sexually-reproducing unicellular or multicellular organisms.

Please help me come up with an answer for this question thankyou so much! Compare and contrast the processes of cellular respiration and photosynthesis. Think of as many similarities and differences as you can (things to consider: inputs and outputs, the role of energy, the types of organisms that do each process, the location within cells)

Answers

Explanation:

The end result is glucose, with oxygen being the waste product. The two processes are similar in that they both produce energy, albeit in two different forms. They are different in that photosynthesis assembles the glucose molecule, while cellular respiration takes it apart.

Phytoplankton, shown on the left in the image below, are microscopic organisms that can be found in freshwater and salt water environments. They perform photosynthesis to get energy and act as an important food source for larger organisms, such as the whale that is shown on the right. Phytoplankton A large whale. Which characteristic describes the whale but not its food source, the phytoplankton? The whale is heterotrophic. The whale has cell walls. The whale is unicellular. The whale is a prokaryote.

Answers

Answer:

The whale is heterotrophic.

Explanation:

Energy is needed by organisms to perform their life functions. Organisms, in nature, feed on one another for energy source. Some organisms are, however, capable of synthesizing their own food or energy source via a process called photosynthesis. This is the case of the phytoplankton in the question. These organisms are, therefore, called AUTOTROPHIC ORGANISMS or PRODUCERS.

On the other hand, some organisms are incapable of this self-production of energy source. Hence, they rely on other organisms for it. These category of organisms are called HETEROTROPHIC organisms, which is the category the large whale fall into due to its dependence on phytoplankton for energy source.

You go to the circus and see the tiger show. When the trainer cracks his whip, the tiger jumps through the hoop. This is an example of

a. operant conditioning with a positive reenforcement

b. operant conditioning with negative reenforcement

c. operant conditioning with punishment

d. none of the above​

Answers

Answer:

C

Explanation:

the trainer has already threatened and hit the tiger before.

thus, when he cracks the whip, the tiger is afraid and will "volunteeringly" jump through the hoop.

the defination of operant conditioning with punishment is any change in a human or animal's surroundings which, occurring after a given behavior or response, reduces the likelihood of that behavior occurring again in the future.

Larry recalls his first memory of riding a red tricycle at the age of 4. Larry’s memory is: True False

Answers

Answer:

True

Explanation:

False memory refers to remembering an event differently from the way it happened or remembering events that never happened at all.

Larry's memory is a true memory because it doesn't sound like something that could be made up. Also, most children ride tricycles around the age of 4 or even younger.

Hope that helps.

Is your prediction supported by the membrane potential chart?

Answers

Answer:

The membrane potential of a resting neuron is primarily determined by the movement of K+start text, K, end text, start superscript, plus, end superscript ions across the membrane. ... Zero voltage across the membrane, as measured by a voltmeter with one electrode inside and one electrode outside the cell.

Answer:

Yes, it is. The chart shows that the initial charge of the neuron is negative. When the neuron is stimulated, sodium ions enter the cell. So, the voltage inside the cell changes to positive. When potassium ions move outward, the voltage decreases until it reaches its previous state.

Explanation:

what kingdom does fish belongs to? ​

Answers

Answer:

animalia

Explanation:

Essential amino acids are amino acids that must be obtained through the diet. Non‑essential amino acids can be made biosynthetically. Classify the amino acids into either essential or non‑essential amino acids.

Answers

Answer:

Explanation:

There are at present 20 major amino acids produced in the body. These amino acids are important biological components in the body. They are the building blocks of proteins. Also essential in the synthesis of nucleotides including the DNA and RNA. There are different ways of classified these amino acids:

Essential and non essential. The essential amino acids cannot be synthesized from scratch in the body but has to be obtained from our diet, while non essential is produced by the body

Acidic, basic, neutral, polar, non polar etc.

The essential amino acids are arginine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.

While the non essential amino acids are: alanine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, proline, serine, and tyrosine.

botanical name for fals yam​

Answers

Answer:

Icacina senegalensis.

Hope it helps you:)

Answer:

[tex]\boxed{\mathrm{Icacina \:\: oliviformis}}[/tex]

Explanation:

False yam is a root crop found in the Northern part of Ghana.

The botanical name for False yam is Icacina oliviformis.

Saliva is released by __________ and it acts on _______.

Answers

Answer:

Salivary glands, food

Explanation:

Salivary glands release saliva, and it acts on the food and turns into a soft pulpy mass called bolus. Bolus is the simplier form of food which helps in digestion of complex food.

Hope this helps. Mark me as the Brainleist if you want...

Answer:

salivary glands, food

Explanation:

Saliva is released by salivary glands and it acts on food.

Salivary glands produce saliva. The saliva acts on food and creates a soft lump called bolus during the chewing process.

PLEASE HELP ME ASAP BECAUSE IT IS DIFFICULT TO UNDERSTAND. Explain it for me.

Answers

Answer:

C.

Explanation:

For mRNA strands, there are four letters used in their code. A (adenine), U (Uracil), G (guanine), and C (cytosine.)

For RNA, it is the same, but the Uracil is replaced with Thymine (T).

A always pairs with U.

G always pairs with C.

YOUR QUESTION:

The scientist's strand code is has to convert the Thymine to Uracil since it is RNA instead of mRNA.

Hopefully this somewhat helped :)

Drag each tile to the correct box. Arrange the stages of the frog’s life cycle from first to last. ↓ ↓ ↓ ↓

Answers

You didn't put the answer options, but the frog life cycle phases are:

Mating: In this phase two adult frogs, a male and a female, mate in the water or on plates. At this point, the male frog wraps his arms around the female and overlaps over her back. Spawning: At this point, the female releases the eggs into the water, ready to be fertilized by the males. Fertilization occurs outside the female's body. Eggs: Some fertilized eggs will be devoured by small animals, but those that survive will hatch 7-9 days after fertilization, releasing a frog shape, called a tadpole.Tadpole: It is similar to a fish and is formed by tail, mouth and gills. After 7 days of life, you will be able to swim and feed on algae. Four weeks later he will develop teeth and skin. When he reaches 9 weeks he will begin to change his shape, growing in size and developing head and legs. At that moment it will look more like a frog, but it still has a long tail. Metamorphosis of the fish: Up to twelve weeks of age it will reach the shape of a frog and start to feed on insects. Gradually it will lose its tail and its tongue will grow. The 16 weeks will become an adult frog, being able to mate and restart the cycle.

Answer:

The answer is below mark brainlyist

Explanation:

Which of these lymphoid organs destroys bacteria before it can breach the intestinal wall and generates "memory" lymphocytes for long-term memory?

Answers

Answer:

Peyers patches

Explanation:

Peyers patches are group of lymphoid follicles found in the ileum of the small intestine.

This part of lymphatic system form part of immune system that help to control bacteria population in the small intestine and prevent the growth of pathogenic bacteria in the small intestines. It plays an important role in immune surveillance where it recognises pathogenic bacteria and destroy the bacteria.

It is a lymphoid organs destroys bacteria before it can breach the intestinal wall and generates "memory" lymphocytes for long-term memory because it form the part of the immune system which help to fight infection or foreign substances in the body, also by generating lymphocytes which is a white blood cells of the immune system which generate long term memory of foreign pathogens and destroying it.

g 1 molecule of glucose is catabolized to pyruvate and then acetyl-coA. All the acetyl-coA enters the citric acid cycle. How many molecules of NADH are produced from the citric acid cycle only (do not include NADH from glycolysis or the pyruvate dehydrogenase complex in your calculation.) You must answer as a number i.e if you think the answer is 12, you must enter 12, not twelve.

Answers

Answer:

6NADH

Explanation:

In the kreb's cycle NAD is  reduced during the reduction of 6-carbon citrate to 5 carbon Alpha-Ketoglularate.

The second is produced during the conversion of 5carbon alpha ketoglutarate to succinate. Lastly in  the conversion of fumirate  to oxoloacetate;another NADH  is formed.

However, since two pyruvate enters the Kreb's cycle therefore 6NADH(three NADH per cycle of Citric)  are produced for each molecule of glucose that is broken down from glycolysis.

Remember,each glucose molecule goes through 2 cycles of Kreb.

Futhermore co-enzyme FADH2 are also produced,with 2 molecules per 1 glucose.

These Co-ezymes transfer hydrogen ions,into the matrix of the mitochondria,where is is splits to protons and  electrons.

The electrons formed the ETC,which produce PMF  for transporting protons into the intramembranes for electrochemical gradients needed to generate energy for ATP s synthesis,by ATP synthase.

.

Please help!!!!! science, please explain in sentence cause yes i don’t know where to find these answers !

Answers

Answer:

1. DNA replication.

2. rRNA - is called the ribosomal RNA which serve as structural components of protein-making structures known as ribosomes.

mRNA - is called the messenger RNA which serve as temporary copies of the information found in DNA.

tRNA - is called transfer RNA, that ferry amino acids to the ribosome to be assembled.

3. Protein synthesis.

Explanation:

Hope it helps.

interact to produce a trait in which neither dominant gene can produce its effect in the presence of the other.
O Multiple alleles
Chromosomes
O Carriers
Sex linked genes

Answers

The answer is multiple alleles

Answer:

A

Explanation:

) Recall what you know about crossing over, independent assortment, and random joining of sex cells during sexual reproduction.

Answers

Answer:

Crossing over is the process of interchange of genetic information among non-sister chromatids of homologous chromosome pairs during meiosis (specifically during synapsis in prophase I). During this process, the synaptonemal complex enables the interchange of chromosome fragments between non-sister chromatids through crossing over. Moreover, in sexual reproduction, the zygote diploid cell can be generated by the random joining of fully differentiated haploid gametic cells (male and female gametes). The combination of random joining with the phenomenon of crossing over is known to considerably increase the genetic variation of the resulting offspring. After zygote formation, the successive cycles of cell divisions during embryonic development will develop an organism that during its adult stage will reproduce via sexual reproduction.

The general function of an enzyme in the body is to ________. The general function of an enzyme in the body is to ________. eliminate waste products from the blood act as a reactant in carbohydrate storage catalyze chemical reactions maintain homeostasis maintain a neutral pH

Answers

Answer:

catalyze chemical reactions

Explanation:

An enzyme is a proteinous substance that acts as biological catalysts and increases the rate of biochemical reactions in the body. Enzymes are specific in nature which is as a result of the structure/shape of its building block (amino acid).

Enzymes speedens the rate of a chemical reaction in living systems, which would normally not occur or occur at a much slower rate, without the presence of an enzyme. Enzymes acts on the reactants called Substrates by binding to them to form products but they are not used up in the reaction. Hence, enzymes are not reactants.

Prokaryotes, like most living organisms, need movement to locate food and to survive.

Answers

Answer:

Explanation:

Prokaryotes, like most living organisms, need movement to locate food and to survive. If a prokaryote needed to move to a new food source, which structure would it use for locomotion?


what is the importance of autotrophic organisms for other organisms?

Answers

Answer:

the importance of autotrophic organisms with respect to energy flow and nutrient cycling in ecosystems. Primary producers usel solar or chemical energy to manufacture their own food and they use this energy through cellular respiration and growth and reproduction--energy used for NPP.

In 1998, paleoanthropologist Rick Potts published an article in The Yearbook of Physical Anthropology, a peer-reviewed journal. The article was titled “Environmental Hypotheses of Hominin Evolution.” In his paper, Potts claimed that great variations in environmental conditions over time were responsible for the adaptability of humans and the success of our species. Which would most likely be found in his paper? a review of modern human anatomical structure evidence of changing environmental conditions, with references the reasons competing hypotheses are wrong his opinion of what will happen to the survival of the human race

Answers

Answer:

Dr. Potts used environmental data to support environmental hypotheses capable of explaining human evolution  

Explanation:

In this paper, the author stated that environmental factors have been fundamental for the emergence of adaptive traits during human evolution. In consequence, Dr. Potts explained how particular environmental factors and habitats might have shaped human evolution. For example, it has been hypothesized that dry savanna vegetation might have been a key environmental factor associated to the emergence of human traits including, among others, bipedality, making of tools from stones, the development of human brains, etc. In order to prove this hypothesis, the author recorded environmental data from different regions in Africa (Olorgesailie, Olduvai, Turkana, Zhoukoudian, etc), where it is believed that first hominids evolved about 6-8 million years ago.

ITS NOT B AND ITS NOT C

SOOO EITHER D OR A

Explanation

What type of molecule is represented by the model below? A molecule made up of four carbon rings with other atoms bonded to those rings. Fat Carbohydrate Steroid Protein Points earned on this question: 0

Answers

Answer:

Steroid

Explanation:

Steroids are molecules that usually have 17 carbon atoms distributed in four rings of carbon bonded together and linked to atoms of other elements, as shown in the aciam figure. Steroids are molecules soluble in fat and are produced synthetically for therapeutic and even aesthetic purposes, however their use must be monitored by a responsible professional.

Answer:

STEROID

Explanation:

Steroids are molecules that usually have 17 carbon atoms distributed in four rings of carbon bonded together and linked to atoms of other elements, as shown in the aciam figure. Steroids are molecules soluble in fat and are produced synthetically for therapeutic and even aesthetic purposes, however their use must be monitored by a responsible professional.

I neeed help pls answe them plssss

Answers

Answer:

Autosomal dominant and recessive: Autosomal dominant states a pattern of inheritance in which an individual carries one normal gene and one copy of a mutant gene while autosomal recessive states a pattern of inheritance in which an individual have two copies of the mutant gene.

Incomplete dominance:  Incomplete dominance states a heterozygous condition in which both the alleles present are partially expressed and produces intermediate phenotype.

Codominance: In codominance and individuals receive alleles, if both the alleles are different including dominant and recessive, dominant allele will be expressed while recessive will be masked.

Multiple alleles: organisms with multiple alleles exist with two copies of every gene present in a population with variation in genes.

Sex linked gene: In humans and some other organisms, sex linked genes are influenced by genes on the X chromosome. for example: If a gene is present on the X chromosome only and not the Y chromosome.

Other Questions
An investor considers investing $10,000 in the stock market. He believes that the probability is 0.30 that the economy will improve, 0.40 that it will stay the same, and 0.30 that it will deteriorate. Further, if the economy improves, he expects his investment to grow to $15,000, but it can also go down to $8,000 if the economy deteriorates. If the economy stays the same, his investment will stay at $10,000.a. What is the expected value of his investment?b. Should he invest the $10,000 in the stock market if he is risk neutral?c. Is the decision clear-cut if he is risk averse? Explain. Find the value of x for the triangle.37374545 Which statement most accurately describes a conflict of commitment? It involves a monetary gain by one party over another party. It occurs when outside activities interfere with ones responsibilities to an employer. It occurs when an institution does not follow the financial rules from a funding source. It can only occur between an institution and an outside organization. figure out if the equation is inverse or direct Determine the length of the cantilevered beam so that the maximum bending stress in the beam is equivalent to the maximum shear stress. What is the surface area of the rectangular pyramid below? 13,13,13 The aggregate demand and aggregate supply model is a useful simplification of the macroeconomy used to explain short-run fluctuation in economic activity around its long-run trend.a) The vertical axis of a diagram of the aggregate demand and aggregate supply curves measures which of the following?A. An economy's price level.B. The amount of a particular representative good produced in the economy.C. The price of a particular representative good produced in the economy.b) Which of the following are reasons that the short-run aggregate supply curve slopes upward?A. As the price level rises, firms expand their production because they can sell their output for more money.B. As the price level rises, firms find it more profitable to hire workers at any given wage.C. As the price level rises, firms decrease their investment, because it is more expensive to purchase capital. Use the De Morgan law that states: ~(p q) is equivalent to ~ p ~ q to write an equivalent English statement for the statement. It is not the case that a gun and a nose are both weapons. A gun is not a weapon or a nose is not a weapon. guns are not noses. A gun is a weapon but a nose is not. A gun is not a weapon and a nose is not a weapon. please answer asap. there are two pics :) Case-Based Critical Thinking Ryan is creating a website for an automobile company. He wants to include media files on the web page and make the page appealing to the viewers. 43. Ryan wants a particular embedded media clip to automatically restart when it has finished playing. Which of the following HTML audio and video element attributes must Ryan include in his code to accomplish this?a. src. b. loop. c. controls. s. preload. Please help with the questions on the picture, it's very urgent......Thank you Mr. and Ms. Kingsley owned acre as joint tenants in fee simple absolute. Ms Kingsley secretly conveyed her interest to herself in an instrument that added, "I hereby terminate the joint tenancy in Black-acre with Mr. Kingsley." Ms. Kingsley thereafter leased a portion of the property to Mr. Matthew, over the objections of Mr. Kingsley for Mr. Matthew to use for holding boxing matches. Their lease provided that Mr. Matthew would pay $1000.00 on the first day of each month during which he was permitted to use the property. Mr. Kingsley demanded from Ms. Kingsley one-half of the rents received from Mr. Matthew.Required:Describe the property relations between the parties and Mr. Kingsley's rights and remedies. Write 2 paragraphs comparing the society atyour locality at present and the society 50 years. A deep-sea diver is in search of coral reefs.he finds a beautiful one at an elevation of -120 4/7feet. While taking pictures of the reef he catches sight of a manta ray. He swims up 25 3/7feet to check it out.what is the diver's new elevation? Consider a product with a daily demand of 600 units, a setup cost per production run of $200, a monthly holding cost per unit of $5.00, and an annual production rate of 300,000 units. The firm operates and experiences demand 300 days per year.Required:a. What is the optimum size of the production run? b. What is the average holding cost per year? c. What is the setup cost per year? d. What is the total cost per year if cost of each unit is 10 dollars? e. Suppose that management mistakenly used the basic EOQ model to calculate the batch size instead of using the POQ model. How much money per year has that mistake cost the company? Your aunt was always very careful during her trips abroad. A) No tener ni pies ni cabeza Your friend was able to figure out the way back to the camp just by looking at the stars. B) Andar con pies de plomo The child told us a story that made no sense at all. C) Dormir a pierna suelta The flight to Asia took 14 hours, but I slept for 8 uninterrupted hours. D) Dar en el blanco A charge is placed on a spherical conductor of radius r1. This sphere is then connected to a distant sphere of radius r2 (not equal to r1) by a conducting wire. After the charges on the spheres are in equilibrium:__________.1. the electric fields at the surfaces of the two spheres are equal. 2. the amount of charge on each sphere is q/2. 3. both spheres are at the same potential. the potentials are in the ratio V2/V1 = q2/q1. 4. the potentials are in the ratio V2/V1 = r2/r1 . How do gases responsible for acid rain get into the atmosphere Is Natural law theory is inconsistent with a theory of human rights. True / False A 400 mL sample of hydrogen gas is collected over water at 20C and 760 torr the vapor pressure of water at 20C is 17.5 torr. what volume will the dry hydrogen gas occupy at 20C and 760 torr?