Match the following enzymes involved in DNA replication with their functions.

a. DNA ligase
b. DNA polymerase
c. DNA gyrase
d. helicase

Answer:

DNA ligase is an enzyme which can connect two strands of DNA together by forming a bond between the phosphate group of one strand and the deoxyribose group on another.

DNA polymerase is an enzyme that synthesizes DNA molecules from deoxyribonucleotides, which are the building blocks of DNA. The enzymes play an essential role in DNA replication, usually working in pairs to produce two matching DNA stranges from a single DNA molecule.

DNA gyrase is an essential bacterial enzyme that catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA

Helicases are enzymes that bind and may even remodel nucleic acid or nucleic acid protein complexes. There are DNA and RNA helicases. DNA helicases are essential during DNA replication because they separate double-stranded DNA into single strands allowing each strand to be copied.

Explanation:

DNA ligase seals the fragment, DNA polymerase adds a new nucleotide, DNA gyrase unwinds the DNA, and helicase makes a dent in double helix.

DNA replication is the physiological method that generates two identical replicas of DNA from a single original DNA molecule in molecular biology.

DNA replication takes place in all living organisms and is the most important component of biological inheritance.

Helicase, primase, DNA polymerase, and ligase are the four main enzymes that aid in DNA replication.

Many proteins and enzymes play a role in DNA replication, including: Topoisomerase: This enzyme relaxes the super-coiled nature of DNA. Helicase: Helicase is a protein that separates the two strands of DNA at the replication fork.

The fragment is sealed by DNA ligase, a new nucleotide is added by DNA polymerase, the DNA is unwound by DNA gyrase, and a dent in the double helix is made by helicase.

Thus, this can be the match for the given scenario.

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F
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