The p53 gene is important to the cell cycle in G1 and G2, and cancer. What happens to the cell cycle when a mutation occurs in the p53 gene?
(please no links!!)

Answers

Answer 1

Answer:

PFFT this might help? sorry if not mate

Explanation:

Cell cycle checkpoint controls play a major role in preventing the development of cancer [see Sherr, 1994, for a more detailed discussion]. Major checkpoints occur at the G1 to S phase transition and at the G2 to M phase transitions. Cancer is a genetic disease that arises from defects in growth-promoting oncogenes and growth-suppressing tumor suppressor genes. The p53 tumor suppressor protein plays a role in both the G1/S phase and G2/M phase checkpoints. The mechanism for this activity at the G1/S phase checkpoint is well understood, but its mechanism of action at the G2/M phase checkpoint remains to be elucidated. The p53 protein is thought to prevent chromosomal replication specifically during the cell cycle if DNA damage is present. In addition, p53 can induce a type of programmed cell death, or apoptosis, under certain circumstances. The general goal of p53 appears to be the prevention of cell propagation if mutations are present. The p53 protein acts as a transcription factor by binding to certain specific genes and regulating their expression. One of these, WAF1 or Cip1, is activated by p53 and is an essential downstream mediator of p53-dependent G1/S phase checkpoint control. The function of p53 can be suppressed by another gene, MDM2, which is overexpressed in certain tumorigenic mouse cells and binds to p53 protein, thus inhibiting its transcriptional activation function. Other cellular proteins have been found to bind to p53, but the significance of the associations is not completely understood in all cases. The large number of human cancers in which the p53 gene is altered makes this gene a good candidate for cancer screening approaches.


Related Questions

please help with my biology

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Pretty sure it is the 3rd one

SOMEONE PLS HELPPPP!!!!!!!!!! TIMED

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Answer:

8.C

10.A

11.a

Explanation:

in
18
An unborn child receives
antibodies from its mum before
.birth
What type of immunity is this an
?example of
natural active immunity
artificial active immunity
natural passive immunity
artificial passive immunity

Answers

Answer:

d...........................

The pistil collects pollen from the __________.
A. seed
B. ovule
C. sepal
D. stamen

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Answer:

Stigma

Explanation:

Stigma – The head of the pistil. The stigma receives pollen, which will begin the process of fertilization.

Hope this helps!

Natural selection will only lead to evolution if it allows for an organism to:

a) Possess advantageous traits
b) Compete for resources
c) Produce offspring
d) All of the above

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d)all of the above i think

7.
Finches on the Galapagos Islands express a variety of traits. Variability in the offspring of these finches is a result
of

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Answer:

Meiosis and mutation

Explanation:

Meiosis because that is the result of how you get genes.

Mutation because that is acctually how you would get that specific gene or variability in the offspring.

At which stage of this food chain will there be the smallest number of organisms
found? *
a. Aphid
b. Toad
c. Snake
d. Rosebush

Answers

I think the answer is D. Rosebush
I think c snake but I’m not completely sure

You observe that embryos from two different organisms have similar features. What reasonable conclusion can you make?

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You can conclude that the organisms have a common ancestor.

Answer:

common ancestor

Explanation:

Which landforms do you find at convergent boundaries?


A. trenches and a rift valley

B. rift valley and mid ocean ridges

C. mountains and trenches

D. mid ocean ridges and mountains

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Answer:

A

Explanation:

because they go against each other

A. Would be 100% correct

What phase change is shown in the image


1. melting
2. freezing
3. condensing
4. ionization

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Answer:

Melting

Explanation:

A solid block transformed into a liquid. The base lost its structure.

Help me please I feel dead inside

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Answer:

A

Explanation:

I would go with A. "Because.. blah etc".

Answer:

Video games are the reason children are interested in learning

Explanation:

It would motivate most kids to learn, which is a benefit for classrooms/teachers

water in plants can be lost through what​

Answers

Answer:

transpiration

Explanation:

Transpiration is the process of water movement through a plant and its evaporation from aerial parts, such as leaves, stems and flowers. Water is necessary for plants but only a small amount of water taken up by the roots is used for growth and metabolism. The remaining 97–99.5% is lost by transpiration and guttation.

I hope my answer will help you keep safe

Which person would most likely be biased about
how plastic waste affects the environment?
O A. The owner of a plastic-making company
B. The owner of a car
O C. A gas-station employee
O D. A scientist studying plastic

Answers

I believe its A i hope that helps

Importance of flower and herbal farming

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Answer:

Medicinal plants are considered as a rich resources of ingredients which can be used in drug development either pharmacopoeial, non- pharmacopoeial or synthetic drugs. A part from that, these plants play a critical role in the development of human cultures around the whole world.

The major use of herbal medicines is for health promotion and therapy for chronic, as opposed to life-threatening, conditions. However, usage of traditional remedies increases when conventional medicine is ineffective in the treatment of disease, such as in advanced cancer and in the face of new infectious diseases.

- found it online

Explanation:

hope this helps

Answer:

Medicinal plants are thought to be a rich source of ingredients that can be used in the development of pharmaceutical, non-pharmaceutical,, or synthetic drugs. Aside from that, these plants play an important role in the development of human cultures all over the world. Flowers are important in nature because they can feed insects, birds, livestock, and humans; they can provide natural remedies for humans and certain animals; and they can help in plant reproduction by attracting outside pollinators. Plants would be only green in the absence of flowers, and the earth would be a duller place.

Explanation:

Scientists discover a new organism. The organism is an autotrophic multicellular organism. To which of
these kingdoms does this organism most likely belong?

Answers

Answer:

you diddnt include the answer choices but from just what i know autotrophs usually belong to algae

Explanation:

In the Arctic marine habitat, fishing has long been a way of life. Natives to the area have satiably utilized the riches of the oceans for generations. Recently a commercial fishing company has entered this area and begun bottom trawling for small fish such as sardines and Arctic cod. How would such a fishing technique impact the ecosystem? Choose ALL that apply. A) Top level predators may leave the area in search of food. B) Overall, there will be a reduction in biodiversity in the area. C) Once prey species are caught, the food web in the area will be disrupted. D) Predators from other regions will move in to replace absent polar bears and seals. E) The trawl net will scoop up everything in its path, including marine life and seafloor structure.

Answers

Answer: A, B, C, E

Explanation: USA test prep

The Arctic marine habitat comprises diverse ecosystems such as special ice berms, long year sea ice, etc. Therefore applicable statements are A, B, C and E.

Why is the Arctic habitat important?

The Arctic is a special ecosystem with a complex food web made up of organisms acclimated to its harsh conditions.

It supports multiple large fisheries and massive populations of roaming birds that come to the Arctic in the summer to mate.

Thus, options A, B, C and E are correct, whereas the remaining option is incorrect according to level of organization.

To learn more about the Arctic ecosystem click here:

https://brainly.com/question/25948550

At the end of the egg experiment, the egg was placed in water. What type of solution was this?​

Answers

Answer:

Hypotonic

Explanation:

The egg has more solutes than the water so water will rush into the egg through osmosis. Therefore, this is a hypotonic solution. Hope this helps!

Please hellllpppp!!!! Pleaseee!

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Answer:

Option. B

Explanation:

3) Give one function of Meibomian gland:​

Answers

Answer:

abnormal gland function. As we know, the meibomian glands secrete the meibum responsible for the formation of the tear film's outer layer. The meibum aids in reducing the evaporation of tears from the front surface of the eye, increasing the surface tension and forming an optically superior tear meniscus.

Anatomy
Hope this helps ♥️

These genes are passed on to offspring as dense structures of DNA known as

A. Chromosomes
B. Chromatin
C. Proteins
D. Polymerase

Answers

Answer:

A. Chromosomes

Explanation:

Natural gas burns
cleaner than coal, yet it is considered a pollutant. Why?

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Answer:

Cleaner burning than other fossil fuels, the combustion of natural gas produces negligible amounts of sulfur, mercury, and particulates. Burning natural gas does produce nitrogen oxides (NOx), which are precursors to smog, but at lower levels than gasoline and diesel used for motor vehicles.

meiosis results in genetic variation than asexual reproduction because it​

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Answer:

allows the recombination of genetic information.

Explain why there must be at least one barrier to reproduction in order for speciation to occur

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Answer:

Speciation occurs when a single species becomes two or more separate species, which can no longer interbreed with one another. Reproductive isolation is required for speciation. Reproductive isolation means the groups in question cannot mate with one another, often because of physical barriers.

Answer:

Speciation occurs when a single species becomes two or more separate species, which can no longer interbreed with one another. Reproductive isolation is required for speciation. Reproductive isolation means the groups in question cannot mate with one another, often because of physical barriers.

Explanation:

Write 4 paragraphs and thank you

Answers

There is something new! There is now 5 seasons instead of 4. Everyone is really happy. It is called the second summer. This is pretty cool because summer does not last very long, and with a second summer it could last longer.

Some people might not enjoy having a longer summer though. It is a big change for everyone. Me and my friends like summer because there is more time for us to do things together, and spend more time together. Summer is fun for a lot of people for example, there is no school. When you dont have school it makes more time for people to spend with family and friends.

If there is a second summer there is more time to spend outside, with friends, going on trips with family, and lots of other things. This is because there would be more time off school. If there was more time off school then there is more free time to do what ever you want. But.... some people do not like summer as much as others. The people that dont really like summer would just have to get used to it. There is nothing you can do that is part of earths rotation.

So if there is 5 seasons now, no one can change it. They can not change it because no one can rotate or tilt the earth. The earth tilts when it is changing seasons. No one can just go up and tilt the earth so they could have the season they want. But that is what i think would be cool if there were 2 summers. Also during summer is when family, and Friends can plan vacations. So people could go on vacation more to!

this is the best I can do❤❤

Match the key choices with the appropriate description​

Answers

Answer:

I don't know, thanks for the point

Horses get their energy from eating grass and oats. Florida panthers get energy from eating deer and raccoons. Raccoons get energy from eating frogs and fruit. Bobcats get their energy eating lizards and birds. Which animal above is an herbivore?

Horse
Bobcat
Panther
Raccoon

Answers

A tiger rawrrrrrrrrrr

Answer: Horse

Explanation:

Its the only one who eats plants

What do carbohydrases break down?

Answers

Answer:

Explanation:

Carbohydrase enzymes break down starch into sugars. The saliva in your mouth contains amylase, which is another starch digesting enzyme. If you chew a piece of bread for long enough, the starch it contains is digested to sugar, and it begins to taste sweet.

describe the type of organisms that are classified into the achaea domain

Answers

Answer: Archaea, (domain Archaea), any of a group of single-celled prokaryotic organisms (that is, organisms whose cells lack a defined nucleus) that have distinct molecular characteristics separating them from bacteria (the other, more prominent group of prokaryotes) as well as from eukaryotes (organisms, including plants and animals, whose cells contain a defined nucleus).

Nitrogen levels were found to be very high in a local farm pond. The pond became full of algae and the fish in the pond started to die. What probably caused an increase in nitrogen in the water?

A. Warm weather

B. Nitrogen-fixing bacteria

C. Fertilizer runoff

D. Overfishing

Answers

Maybe it’s C not sure but I’ll check again I hope so

what factors are needed to create a storm?

Answers

Answer:

For a storm to be created, it needs warm sea surface temperatures, light winds, and rotation or spin. If any of the following does not happen, the storm will either weaken or decay.

Hope this helps! :)

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