Answer:
Thyroid hormones
Explanation:
Animals and people exposed to pesticides such as insecticides, fungicides, and herbicides, have shown to be affected by their effect on the thyroid. These chemicals can produce endocrine alterations acting as thyroid disrupters. They affect many mechanisms in the organisms such as inhibition of thyroid iodine uptake, interference with the thyroid hormone receptor, binding to transport proteins, among others. They cause toxicity in the functioning of the hypothalamic-pituitary-thyroid axis.
There are many studies that associate thyroid diseases with exposure to organochloride pesticides. Significant alteration in the TSH, T3, and T4 levels have been expressed by people directly or indirectly exposed to the chemicals.
Look at the phylogenetic tree. Do robber crabs have more in common with humans or with sponges? What conclusion can you reach about their evolution?
Answer:
Robber crabs have more in common with humans than sponges.
Explanation:
Robber crabs have more in common with humans than sponges because sponges don't have tissues. Crabs and humans have specialised tissue.
Answer:
Hope this helps! From Plato
Explanation:
Robber crabs have more in common with humans, which are vertebrates. Sponges are simple organisms that don’t have tissues. Crabs and humans have specialized cells and tissues, bilateral symmetry, and a coelom. According to the phylogenetic tree, vertebrates and arthropods have more nodes, or common ancestors, than crabs have with sponges.
In fruit flies the allele for red eyes, R, is dominant. Witch genotype represents a white eyed male fruit fly
Answer:
rr
Explanation:
Dominant alleles will always be visible on a creature if they are at all present, such as with brown eyes in humans (i.e. Rr or RR). People with blue eyes (or fruit flies with white eyes) possess two recessive alleles (rr), which is the only way for a recessive trait to be present.
In fruit flies, the allele for red eyes, R, is dominant. Which genotype represents a white-eyed male fruit fly?
The answer is XrXr
Classify each nutrient as a macronutrient or as a micronutrient
Answer:
Macro: Phosphorous, Protein, Fat, Carbohydrates
Micro: Vitamin A, Sodium
Explanation:
Macronutrients are nutrients that are needed in large amounts. Micronutrients are needed in smaller amounts.
You are doing an experiment in which you are using an in vitro translation system derived from rabbit reticulocytes, called a rabbit reticulocyte lysate, to translate mRNA in a test tube. The rabbit reticulocyte lysate contains ribosomes, translation initiation and elongation factors, tRNAs, aminoacyl tRNA synthetases, release factors, amino acids, and ATP. The lysate does not contain any mRNA, so you must add the mRNA you would like to translate to the system. A. When you analyze the proteins made from your lysate, you find that they are all only two amino acids long. At first, you think that there must be a mutation to a stop codon in the position of the third codon, so you do another experiment with a different mRNA. Again, all the newly synthesized proteins are only two amino acids long, so you conclude that there is a problem with some component in your lysate.
Describe ONE possible problem in the translation system (lysate) that would result in the limitation of newly synthesized peptides to two amino acids in length.
Answer:
Problems with transfection efficiency or absence of essential mRNA modifications (capping and poly-A tail)
Explanation:
Translation is the process of protein synthesis from RNA in which the genetic information encoded in a messenger RNA (mRNA) molecule is translated into a protein sequence composed of amino acids. Translation has three steps: initiation, elongation, and termination. During translation, different elements are required to initiate, continue and complete the process, which include essential molecules such as amino acids, mRNA, tRNAs, ribosomes, energy-carrying molecules (i.e., ATP, GTP), initiation factors (i.e., eIF1A, eIF3, etc) and elongation factors (eEF-2, EIF5A). For example, humans can't synthesize nine essential amino acids (i.e., threonine, tryptophan, phenylalanine, valine, methionine, leucine, histidine, isoleucine, lysine), thereby it is imperative to include these amino acids to synthesize proteins composed of them. On the other hand, it is also fundamental to take into account that the efficiency of transfection of the molecules required during translation, as well as the absence of modifications in the mature mRNA sequence, may alter the process in vitro.
Which type of organism developed first?
al
answer: algae
explanation: because the were the first ones to adapt with water and land...
I'm confused on labelling the stages of mitosis in these onion cells. I know what these stages look like illustrated in the textbook, but am confused when looking at actual slides of cells. Can anyone help? Photo is attached.
Answer:
Hello. I numbered your cells to make it easier to name them. The image with the numbers is attached.
cell 1: Interphase.
Cell 2: Telophase.
Cell 3: Metaphase.
Cell 4: Prophase
Cell 5: Interphase.
Cell 6: Anaphase.
Explanation:
In the interphase, it is possible to notice that the cell increased its volume, due to the increase in the size of the organelles and the increase in the number of the organelles, which indicates the beginning of the cell cycle.
Prophase is really the beginning of the cell cycle. At that moment, you can see that the nuclear membrane has been disorganized and we can see a 'tangle' of the cell interior that is very full and disorganized. This is mainly because the material present in the nucleol spreads through the cell.
In the metaphase, the chromosomes are condensed and start to connect to each other forming the spindle fibers, which are located right in the middle of the cell, forming the equatorial plate.
In anaphase there is a rupture of the centromeres and sister chromatids. Each part of these elements migrates to one of the poles of the cell. This is mainly due to the shortening of the spindle fibers.
Telophase is the final phase of the cell cycle, at that moment, the spindle fibers disappear, the chromosomes are condensed and the nuclear membrane is reconstructed. However, the cell has not yet separated and it is possible to see two nuclei in a single cell, each nucleus is at a pole, indicating that the division will occur.
What substance are the bacteria (microorganisms) breaking down in the digestive system of cattle? Describe the digestion of this substance.
Answer:
The Bacteria or microorganisms are present in the rumen of cattle that aid in the digestion of cellulose and grains in the digestive system of cattle.
The process of digestion of cellulose by bacteria in cattle is anaerobic digestion and includes two steps – the production of the required enzymes and the fermentation.
In the fisrt step of production of enzyme, the microbes or bacteria are found in the first chamber of the stomach. These bacterias or microbes releases several enzymes that helps in splitting the cellulose into smaller carbs such as glucose.
These smaller carbs are the move to thrd chamber of the stomach and fermented. the required nutrients are absorbed. The digested food then finally reached at fourth chamber (acidic part), where the remained food is digested and passes to the small and large intestines.
Which statement best describes how Watson and Crick's model used other scientists work to create a model of DNA?
They used Chargaff's rule to determine that it contains ribose sugar
O They used Franklin's photo to determine that DNA was a double helix.
They used Levene's work to determine the number of base pairs in each strand.
O They used Nirenberg and Matthei's studies to determine that DNA is made of nucleotides.
Answer:
b.
Explanation:
They used Franklin's photo to determine that DNA was a double helix.
The best statement that describes how Watson and Crick's model used other scientists' work to create a model of DNA can be seen in the second Option.
They used Franklin's photo to determine that DNA was a double helix.
The early 1950s saw the development of the renowned model of the DNA double helix by American scientist James Watson and British physicist Francis Crick. They were the explorers to pass the finishing line in this scientific race.
Rather than doing fresh tests and experiments in the lab, Watson and Crick primarily gathered and evaluated existing data, combining it in novel and illuminating ways.
Franklin was a specialist in X-ray crystallography, a sophisticated approach for identifying molecular structures. When an X-ray beam strikes the crystallized form of a molecule, e.g the DNA, part of the rays are redirected and diverted by the atoms in the crystal, creating a diffraction pattern that unveils data information regarding the structure of the molecule.
Franklin's crystallography provided crucial hints to Watson and Crick on the structure of the DNA model. Some of them originated from Franklin's extraordinarily clear and stunning X-ray diffraction photo of DNA.
According to the work of Phoebus Levene, Levene only posits that the DNA was formed of subunits called nucleotides.
Erwin Chargaff speaks volumes on the determination of the composition of ribose sugar bases.
Therefore, we can conclude that Watson and Crick knew about all these Phoebus Levene and Erwin Chargaff postulates and experiments but it was Franklin's work on X-ray diffraction photos of DNA that gave them a crucial hint to create a model for the DNA.
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Question 8 (5 points)
Which of the following best describes the mechanism by anti depressant
medications function?
Provide a positive rush of the neurotransmitter dopamin-
Made of artificial neurotransmitters that generate exciter
O Allow the body to prochyce more neurotransmitters such a
serotonin
Answer:
Help maintain a balance in neurotransmitters such as serotonin
Explanation:
Anti-depressant medications help the body maintain a balanced, homeostasis level of neurotransmitters, often serotonin.
Human activities, including the use of fossil fuels, have contributed to global
warming and the rise in sea levels. Both of these environmental changes are
threatening ecosystems and human communities worldwide. How could
scientists best cooperate to use scientific research to mitigate this problem?
A. They could look at trends in climate change to predict regions of
concern.
B. They could set regulations in their own countries to protect local
resources.
C. They could make personal choices that help reduce their carbon
footprints.
D. They could study climate change on other planets to predict its
effects on Earth.
Answer:
1 C when carbon footprint are reduced
It will reduce the rate of global warming
They could make personal choices that help reduce their carbon
footprints.
A carbon footprint is the total amount of greenhouse gases including carbon dioxide and methane that are generated by actions.What is carbon footprint?Carbon footprint, amount of carbon dioxide emissions associated with all the activities of a person or other entity like building. It includes- Direct emissions, such as those that result from fossil-fuel.
- Heating and transportation.
- Emissions required to produce the electricity.
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Which is correctly paired?
a. Ascaris - Monoecious
b. Loligo - Conotoxin
c. Ophiuroidea - Autotomy
d. Tridacna Gigas - Gastropod
e. Limulus - Book Lungs
Answer:
The correct option is E: Limulus - Book Lungs
Explanation:
The structure of a book lung is made so as to maximize the efficiency of gaseous exchange in arachnids. An externally located structure, book gills, aids in this process. Limulus are horseshoe crabs that still makes use of book gills. Its a marine creature (an arthopod, to be specific) that has 5 pairs of book gills on its body.
explain why a father with blood group AB cannot donate for a child with blood group O when he marries a woman with blood group O
The odds are astronomical for a father with AB(IV) to have an O(I) child. The only possible way for this phenomenon to occur is if there was a nondisjunction in the ovogenesis for the 9th chromosome and the father also had a nondisjunction for the same chromosome(A sperm cell with no 9th chromosome fertilized an ovum with two 9 chromosomes).
A person with AB cannot donate to a person with O because the receiver has antibodies(alpha and beta) that bind to the antigens on the AB blood cells, causing death.
Why does deleting just one nucleotide cause a dramatic change in the amino acid sequence produced by translation
Answer:
The deletion changes the genetic code.
Explanation:
The sequence of nucleotides determines the order of amino acids in a protein, the order of amino acids determines the shape and the shape determines the function. A very good example of one misplaced nucleotide having tremendous effects is sickle cell disease, where thymine is replaced with adenine(CAC instead of CTC). It means that glutamic acid is replaced with valine. This alters the shape of the protein(Beta chain of hemoglobin). So the red blood cells are deformed and carry a lot less oxygen leading to a lot of symptoms just because of one misplaced letter.
A 26-week-old baby was brought to the pediatric clinic because of increasing lethargy and cyanosis. The infant has been in good health at birth, and the mother had attempted breast-feeding. A blood sample was collected and a positive test for methemoglobinemia was obtained. The baby then was treated with intravenous ascorbate and methylene blue. Within 2 days the child was alert, and the cyanosis had disappeared. It is known that methemoglobin has absorption spectra maxima at 500 nm and 631 nm.
Answer the following questions:
a. What is the chemical difference between hemoglobin and methemoglobin, and how do their oxygen capacities compare?
b. How do you analyze the sample blood to detect methemoglobin?
c. What is the cause of the cyanosis associated with toxic methemoglobinemia?
d. What is the biochemical basis for treatment of toxic methemoglobinemia with ascorbate and methylene blue?
Answer:
a,
This is due to differences in the oxidation states of Fe. atoms present in the two protein pigments.
Generally,the Fe2+ atom in the heme groups is responsible for the oxygen carrying capacities of haemoglobin in RBC.However,in +2 state that Fe carry oxygen through cooperative binding in the blood.When methemoglobin is formed the Fe exits in +3,and therefore can not bind oxygen. Methemoglobin is a mettaloprotein of Fe3+ states. It results from the oxidation of Fe atoms in Hb from Fe2+ to Fe3+ states,during exposure to certain medications,and some nitrate,certain dyes and some compounds.
This can be conducted with CO-oximeter.This is a device used to measure the blood percentage oxygen saturation levels.It conduct this by measuring the oxygen carrying capacity of haemoglobin in a blood sample. Since oxygen saturation levels of a blood sample depends on the amount of Hb,therefore by passing some wavelengths of light across the blood samples,The more the wavelength of lights absorbed by the blood samples, the more the percentage saturation of the blood sample with oxygen,and therefore the oxygen carrying capacity of the blood,thus more Hb.
Hence, if the blood sample absorbs wavelength of light in the range of (500 nm and 631 nm.) it shows that little Hb is present in the blood samples,and the blood should contain Methemoglobin of Fe3+ and not Hb.
Methemoglobinemia is a condition in which methmoglobin concentration of the blood rises,due to the higher percentage of Hb,with F3+( of poor oxygen carrying capacity or uncoupling ) compare to normal F2+ for carrying oxygen. Since these can not transport oxygen,Cyanosis results as the baby turns blue,with lack of oxygen.
Since the rise in the concentration of methmoglobin is the major cause of this condition,reduction of it concentration is the primary step.Therefore, the Methylene blue role is to reduce the amount of methmoglobin by enzyme NADPH-methemoglobin reductase.This occurs with 10-60mints after administration.Thus the concentration of these pigment is reduced,likewise its toxic levels.
Ascorbate can also be used,however a lot of doses is required for this to have a significant effects,and compare to Methylene blue it is less effective.,
Explanation
help asap plss giving branlist
Answer:
Parasitic Relationship
Explanation:
Symbiotic relationship:
is a term that defines an interaction between organisms of different organisms.
Parasitic Relationship:
A relationship in which one organism is benefited and one is not.
Example: A tapeworm living at the gastrointestinal parts.
Mutualistic Relationship:
A relationship in which both organisms benefit.
Example: Egyptian plover bird and the crocodile.
Commensal Relationship:
A relationship in which both organisms are not benefited nor harmed.
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What does environmental quality refer to? Environmental quality refers to the quality of the total environment, including both the natural and the environment.
Answer:
True,
An animal requires, Food, Water, Shelter as basics of life - but I add a third, for social animals; a Mate, Young, or Flock/Herd/Group
Which could best be used to explain why bacteria can infect a person very quickly? outer capsule binary fission protective covering genetic recombination
Answer:
The answer is binary fission.
Explanation:
Binary fission is the process of reproduction by bacteria in which they divide into two cells.
They do this about every 20-30 minutes, this fast rate of reproduction could be best be used to explain why bacteria can infect a person very quickly.
Answer:
B. Binary Fission
Explanation:
Um. BeCaUsE
The citric acid is a stage of catabolism that oxidizes acetate into carbon dioxide and generates energy. There are eight enzymes involved in the citric acid cycle.
1. Which enzymes produce NADH as a product?
a. alpha-ketoglutarate dehydrogenase
b. succinate dehydrogenase
c. malate dehydrogenase
d. isocitrate dehydrogenase
2. Which enzymes produce carbon dioxide as a product? Select all that apply.
a. malate dehydrogenase
b. isocitrate dehydrogenase
c. succinate dehydrogenase
d. alpha-ketoglutarate dehydrogenase
3. Which enzymes produce coenzyme A as a product? Select all that apply.
a. fumarase
b. citrate synthase
c. succinyl-CoA synthesase
d. citraste synthase
4. Which enzymes have an alpha-keto acid substrate? Select all that apply.
a. fumarase
b. alpha-ketoglutarate dehydrogenase
c. citrate synthase
d. malate dehydrogenase
5. Which enzyme catalyzes a hydration reaction?
a. aconitase
b. fumarase
c. citrate synthase
Answer:
1.(a ) alpha-ketoglutarate dehydrogenase
(c) malate dehydrogenase
(d) isocitrate dehydrogenase
2. b. isocitrate dehydrogenase d. alpha-ketoglutarate dehydrogenase
3. b. citrate synthase (c) succinyl-CoA synthesase
4. b. alpha-ketoglutarate dehydrogenase c. citrate synthase d. malate dehydrogenase
5. a. aconitase
Explanation:
The citric acid cycle is responsible for the oxidation of acetyl-CoA produced from pyruvate from glycolysis. The citric acid cycle has eight steps requiring nine enzymatic reactions involving eight enzymes.
The enzymes in the citric acid cycle are: citrate synthase , aconitase, isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase , succinyl-CoA synthesase, succinate dehydrogenase , fumarase , and malate dehydrogenase .
1. The dehydrogenation reactions of isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase , and malate dehydrogenase produces NADH from isocitrate, alpha-ketoglutarate and malate respectively.
2. Oxidative decorboxylation (removal of carbon as CO₂) also occurs in the reactions of isocitrate dehydrogenase and alpha-ketoglutarate dehydrogenase to produce alpha-ketoglutarate and succinyl-CoA respectively.
3. Coenzyme-A (CoA-SH) is produced in the reactions of citrate synthase and succinyl-CoA sythetase to produce citrate and succinate respectively.
4. The enzymes alpha-ketoglutarate dehydrogenase has alpha-ketoglutarate as substrate , whereas citrate synthase and malate dehydrogenase has oxaloacetate as substrate. These substrates are alpha-keto acids.
5. Aconitase catalyzes the conversion of citrate to isocitrate by first a dehydration and then a hydration reaction.
Match each of the following descriptions with the correct term:
a. Located on presynaptic membrane
b. Space between two neurons
c. Contains neurotransmitters
d. Located on postsynaptic membrane
e. Bulbous ending of axon
f. Chemical messenger
1. synaptic cleft
2. neurotransmitter
3. synaptic vesicle
4. receptor
5.axon terminal
6. calcium channel
Answer
a-6
b-1
c-3
d-4
e=5
f-2
Explanation:
The sequence shows synaptic transmission across
The arrival of action potential at the presynaptic neuron,prompted the influx of calcium ions on the presynaptic membrane to the axoplasm.
This leads to the fusion of the synaptic vessels with the post synaptic membrane,These empty their contents of neurotransmitters into the synaptic cleft.
The neurotransmitter e.g acetycholine crosses the cleft to bind with the receptors on the postsynaptic membrane,
The leads to the opening of ligand gated sodium channels which leads to the transmission of the action potential as Post Synaptic Potentials.
This is transmitted along the axon of the postsynaptic neuron,as post synaptic potential which can either be excitatory or inhibitory
Where is the last storage location for melted snow? (2 points) Where is the last storage location for melted snow? (2 points) Group of answer choices Rivers Ocean Streams Mountains
Answer:
Ocean
Explanation:
Ice is usually found in the glaciers in the mountains and once it gets heated it flows down through melting and forms a stream and enters into rivers and these streams combine and lead to the oceans. Thus these oceans become the ultimate storage units of melted snow. Ice and cannot stay in solid-state for too long.Recall what you know about crossing over, independent assortment, and random joining of sex cells during sexual reproduction. Now, go back to the claims in Step 2a. Do you support these claims? If so, do you support the totality of the claims or just parts of the claims? Based on your prior knowledge, make a claim about the factors that cause inherited genetic variations within populations. Also make a claim about the effects of mutations. Write your claim in your notebook. ASAP!!!!
Answer:
Crossing over is a process in which exchange of segments occur.
Explanation:
Crossing over is a process in which two non-sister chromatids of homologous chromosomes exchange the segments of genetic material with each other during meiosis. Due to this process, variation occurs in an organism.
Independent assortment is a process in which different alleles are sorted to different gametes which occurs independently and does not effect one another. This process occurs in metaphase of meiosis l.
Joining of sex cells is a process in which sex cells of male and female join together formed a zygote which turn into a new organism. These sex cells are formed during meiosis which are haploid in nature.
Mutation and crossing over are the factors that cause inherited genetic variations within populations.
Sudden change occurs in the genes of an organism due to the exposure of the cell to radiation or chemicals.
Carbon dioxide molecules diffuse through cell membranes, but many other
substances cannot. A membrane that allows some, but not all, materials to
pass through it is called
Answer:
Semi-permeable membrane
Explanation:
In semi-permeable membranes, only some substances can pass through. Sometimes, some can also pass through the channel protein molecules or transport proteins on the cell membrane.
A cellular structure that is visible with an electron microscope but not with a light microscope is:____________.
1. a mitochondrion.
2. a ribosome.
3. a chloroplast.
4. a nucleus.
Answer:
The ribosome will not be visible with a light microscope
The iris in the human eye contracts and expands, controlling the amount of light that reaches the retina. What types of muscle control this?To which skeletal system does the sternum belong?
Answer:
1. sphincter muscle and dilator muscle
2. Axial skeleton
Explanation:
1.The iris in the human eye is responsible for controlling the exposure of of light that reaches the retina. The movement of iris is controlled by a muscles called sphincter muscle and dilator muscle. sphincter muscle constricts the pupil in bright light while dilator muscle expands the pupil.
2. Sternum belongs to the axial skeleton, which is a long flat bone located in the central part of the chest. Axial skeleton consists of 80 bones and strenum is one of them. Axial skeleton functions to provide protection to vital organs such as brain, heart and lungs. Strenum functions to protect heart.
What process occurs as a zygote becomes a blastocyst?
Answer:
The Answer is B.
Explanation:
The process by which a zygote becomes a blastocyst is cleavage division.Thus, option "B" is correct.
What is fertilization and example?A method of reproduction that entagled the union of male and female germ cell (each with a single, haploid set of chromosomes) to create a diploid cell called zygote.
Thus, option "B" is correct, A group of blastomeres produced by cleavage divisions is known as pre-embryo.
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How is an actual greenhouse similar to the natural greenhouse effect?
Explanation:
That's because the glass walls of the greenhouse trap the Sun's heat. The greenhouse effect works much the same way on Earth. Gases in the atmosphere, such as carbon dioxide, trap heat just like the glass roof of a greenhouse.
A community is a _______________________. Select one: a. group of populations b. group of ecosystems c. group of conspecific organisms d. individual form of life
Answer:
A. group of population
Explanation:
Communities are made up of all the populations of different species in a given area.
Michael, a new lab analyst, receives an email notifying him that his expected samples from a recent outbreak should be arriving soon. To prepare for his analysis, he decides to look into what type of diseases could be spread between animals and humans, as this is a new field for him. Michael has received limited information about the details of the outbreak from the epidemiologists that traveled to the site, but he does know that both animals and humans were infected by some type of virus. Michael looks through some of the lab manuals on how the samples will be handled once in the lab. While reading through these guidelines, he realizes that there are some terms he is not quite sure of. Below are sentences that reflect the terms that Michael had to acquaint himself with while reading through the published guidelines from his laboratory.
Please review the sentences below and fill in the blanks with the correct word(s).
A. arthropods
B. togaviruses
C. encephalitis
D. flaviviruses
E. zoonosis
1. A virus that is able to be transmitted via________ like ticks, flies, and mosquitoes is considered a(n)_______
2. Some arboviruses are able to move through the bloodstream and infect the brains of humans and arbovirus animals. This disease manifestation is called_________
3. A________ is a disease that can be transmitted from animals to humans.
4. Several encephalopathies, such as Eastern equine encephalitis and West Nile virus encephalitis, are caused by the_______ animals such as horses and birds. These viruses can infect humans and animals
1.A arthropods
2.C encephalitis
3.E zoonosis
4.C togaviruses
A person who has Diabetes has difficulty controlling the glucose levels in their blood and must take Insulin to regulate it. Which characteristic of life do they need assistance with?
Based on the given information I believe this will help:
Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Insulin helps keeps your blood sugar level from getting too high (hyperglycemia) or too low (hypoglycemia).
If you have more sugar in your body than it needs, insulin helps store the sugar in your liver and releases it when your blood sugar level is low or if you need more sugar, such as in between meals or during physical activity.
If your body does not produce enough insulin or your cells are resistant to the effects of insulin, you may develop hyperglycemia (high blood sugar), which can cause long-term complications if the blood sugar levels stay elevated for long periods of time.
Treatment:
People with type diabetes cannot make insulin because the beta cells in their pancreas are damaged or destroyed. Therefore, these people will need insulin injections to allow their body to process glucose and avoid complications from hyperglycemia.
CH 7 What will be the effect if a
toxin make a pore ( o ) in the
inner membrane of the
mitochondria
Answer:
Mitochondria is known as the powerhouse of the cell as it provides energy to the cell for performing different functions.
If a toxin causes pore in the inner membrane of the mitochondria and increases the permeability of the mitochondrial membranes. The permeability of mitochondrial membranes leads to mitochondrial swelling and causes cell death through necrosis and apoptosis.